[PDF][PDF] SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

…, J Pan, N Paran, B Perry, M Pingle, J Pinjari, B Politi… - Cell Stem Cell, 2022 - cell.com
Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether
this is a direct effect of the virus. Here, we report that SARS-CoV-2 directly infects kidney …

[HTML][HTML] Diagnosis of imported monkeypox, Israel, 2018

…, Y Wiener-Well, N Paran, B Politi… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
We report a case of monkeypox in a man who returned from Nigeria to Israel in 2018. Virus
was detected in pustule swabs by transmission electron microscopy and PCR and confirmed …

[HTML][HTML] A single dose of recombinant VSV-∆ G-spike vaccine provides protection against SARS-CoV-2 challenge

Y Yahalom-Ronen, H Tamir, S Melamed, B Politi… - Nature …, 2020 - nature.com
The COVID-19 pandemic caused by SARS-CoV-2 imposes an urgent need for rapid
development of an efficient and cost-effective vaccine, suitable for mass immunization. Here, we …

[HTML][HTML] Monkeypox DNA levels correlate with virus infectivity in clinical samples, Israel, 2022

…, M Barlev-Gross, S Karmi, B Politi… - …, 2022 - eurosurveillance.org
The current monkeypox virus global spread and lack of data regarding clinical specimens’
infectivity call for examining virus infectivity, and whether this correlates with results from PCR, …

[HTML][HTML] Detection and infectivity potential of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) environmental contamination in isolation units and …

…, H Achdout, H Tamir, Y Yahalom-Ronen, B Politi… - Clinical microbiology …, 2020 - Elsevier
Objectives Environmental surfaces have been suggested as likely contributors in the transmission
of COVID-19. This study assessed the infectivity of severe acute respiratory syndrome …

[HTML][HTML] Imatinib inhibits SARS-CoV-2 infection by an off-target-mechanism

…, N Paran, Y Yahalom-Ronen, S Melamed, B Politi… - Scientific reports, 2022 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal agent of
the COVID-19 pandemic. More than 274 million individuals have suffered from COVID-19 …

[HTML][HTML] Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity

H Achdout, EB Vitner, B Politi, S Melamed… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the
ongoing coronavirus disease 2019 (COVID-19) pandemic. The continued spread of SARS-CoV-2 …

[HTML][HTML] Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody

…, T Chitlaru, EB Vitner, S Melamed, B Politi… - Nature …, 2021 - nature.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits high levels of mortality and morbidity and …

Elevation in sphingolipid upon SARS-CoV-2 infection: possible implications for COVID-19 pathology

EB Vitner, R Avraham, B Politi… - Life Science …, 2022 - life-science-alliance.org
Understanding pathways that might impact coronavirus disease 2019 (COVID-19)
manifestations and disease outcomes is necessary for better disease management and for …

Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors

…, N Paran, A Payne, B Perry, M Pingle, J Pinjari, B Politi… - BioRxiv, 2020 - biorxiv.org
The COVID-19 pandemic is a stark reminder that a barren global antiviral pipeline has grave
humanitarian consequences. Future pandemics could be prevented by accessible, easily …