Background Late-onset preeclampsia is the most prevalent phenotype of this syndrome;
nevertheless, only a few biomarkers for its early diagnosis have been reported. We sought to …

Preterm labor commonly precedes preterm birth, the leading cause of perinatal morbidity
and mortality worldwide. Most research has focused on establishing a causal link between …

Objectives To identify maternal plasma protein markers for early preeclampsia (delivery <34
weeks of gestation) and to determine whether the prediction performance is affected by …

Regulatory T cells (Tregs) have been exhaustively investigated during early pregnancy;
however, their role later in gestation is poorly understood. Herein, we report that functional Tregs …

Objective Pregnancy is accompanied by dramatic physiological changes in maternal plasma
proteins. Characterization of the maternal plasma proteome in normal pregnancy is an …

Preterm birth remains the leading cause of neonatal morbidity and mortality worldwide. A
substantial number of spontaneous preterm births occur in the context of sterile intra-amniotic …

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of every
4 preterm neonates is born to a mother with intra-amniotic inflammation driven by invading …

Identification of pregnancies at risk of preterm birth (PTB), the leading cause of newborn deaths,
remains challenging given the syndromic nature of the disease. We report a longitudinal …

Objective: To determine whether a soft cervix identified by shear-wave elastography between
18 and 24 weeks of gestation is associated with increased frequency of spontaneous …

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. Inflammation
is causally linked to preterm birth; therefore, finding an intervention that dampens …