User profiles for Bogdan Tanasa
Bogdan Tanasa, MD PhDStanford University Verified email at stanford.edu Cited by 8654 |
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
Antigen stimulation of immune cells triggers Ca 2+ entry through Ca 2+ release-activated
Ca 2+ (CRAC) channels, promoting the immune response to pathogens by activating the …
Ca 2+ (CRAC) channels, promoting the immune response to pathogens by activating the …
Functional roles of enhancer RNAs for oestrogen-dependent transcriptional activation
The functional importance of gene enhancers in regulated gene expression is well established
1 , 2 , 3 . In addition to widespread transcription of long non-coding RNAs (lncRNAs) in …
1 , 2 , 3 . In addition to widespread transcription of long non-coding RNAs (lncRNAs) in …
REGULATION OF TH2 DIFFERENTIATION AND Il4 LOCUS ACCESSIBILITY
Helper T cells coordinate immune responses through the production of cytokines. Th2 cells
express the closely linked Il4, Il13, and Il5 cytokine genes, whereas these same genes are …
express the closely linked Il4, Il13, and Il5 cytokine genes, whereas these same genes are …
lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs
Although recent studies have indicated roles of long non-coding RNAs (lncRNAs) in
physiological aspects of cell-type determination and tissue homeostasis 1 , their potential …
physiological aspects of cell-type determination and tissue homeostasis 1 , their potential …
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
Genome-wide association studies have identified single nucleotide polymorphisms (SNPs)
in the 9p21 gene desert associated with coronary artery disease (CAD) 1 , 2 , 3 , 4 and type 2 …
in the 9p21 gene desert associated with coronary artery disease (CAD) 1 , 2 , 3 , 4 and type 2 …
[HTML][HTML] Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer
Chromosomal translocations are a hallmark of leukemia/lymphoma and also appear in solid
tumors, but the underlying mechanism remains elusive. By establishing a cellular model …
tumors, but the underlying mechanism remains elusive. By establishing a cellular model …
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT
Precise regulation of the NFAT (nuclear factor of activated T cells) family of transcription factors
(NFAT1–4) is essential for vertebrate development and function 1 . In resting cells, NFAT …
(NFAT1–4) is essential for vertebrate development and function 1 . In resting cells, NFAT …
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
While reversible histone modifications are linked to an ever-expanding range of biological
functions 1 , 2 , 3 , 4 , 5 , the demethylases for histone H4 lysine 20 and their potential …
functions 1 , 2 , 3 , 4 , 5 , the demethylases for histone H4 lysine 20 and their potential …
Genome-informed targeted therapy for osteosarcoma
Osteosarcoma is treated with a chemotherapy regimen established 30 years ago. Although
osteosarcoma is genomically complex, we hypothesized that tumor-specific dependencies …
osteosarcoma is genomically complex, we hypothesized that tumor-specific dependencies …
[PDF][PDF] Condensin I and II complexes license full estrogen receptor α-dependent enhancer activation
Enhancers instruct spatio-temporally specific gene expression in a manner tightly linked to
higher-order chromatin architecture. Critical chromatin architectural regulators condensin I …
higher-order chromatin architecture. Critical chromatin architectural regulators condensin I …