[HTML][HTML] Comprehensive analysis of normal adjacent to tumor transcriptomes
…, R Camarda, J Odegaard, H Paik, B Oskotsky… - Nature …, 2017 - nature.com
Histologically normal tissue adjacent to the tumor (NAT) is commonly used as a control in
cancer studies. However, little is known about the transcriptomic profile of NAT, how it is …
cancer studies. However, little is known about the transcriptomic profile of NAT, how it is …
Mortality risk among patients with COVID-19 prescribed selective serotonin reuptake inhibitor antidepressants
Importance Antidepressant use may be associated with reduced levels of several proinflammatory
cytokines suggested to be involved with the development of severe COVID-19. An …
cytokines suggested to be involved with the development of severe COVID-19. An …
Assessment of a deep learning model based on electronic health record data to forecast clinical outcomes in patients with rheumatoid arthritis
…, D Lituiev, M Gianfrancesco, B Oskotsky… - JAMA network …, 2019 - jamanetwork.com
Importance Knowing the future condition of a patient would enable a physician to customize
current therapeutic options to prevent disease worsening, but predicting that future condition …
current therapeutic options to prevent disease worsening, but predicting that future condition …
[PDF][PDF] Microbiome preterm birth DREAM challenge: Crowdsourcing machine learning approaches to advance preterm birth research
Every year, 11% of infants are born preterm with significant health consequences, with the
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …
vaginal microbiome a risk factor for preterm birth. We crowdsource models to predict (1) …
[HTML][HTML] Protected Health Information filter (Philter): accurately and securely de-identifying free-text clinical notes
…, G Schenk, E Rutenberg, B Oskotsky… - NPJ digital …, 2020 - nature.com
There is a great and growing need to ascertain what exactly is the state of a patient, in terms
of disease progression, actual care practices, pathology, adverse events, and much more, …
of disease progression, actual care practices, pathology, adverse events, and much more, …
[HTML][HTML] Deep phenotyping of Alzheimer's disease leveraging electronic medical records identifies sex-specific clinical associations
AS Tang, T Oskotsky, S Havaldar, WG Mantyh… - Nature …, 2022 - nature.com
Alzheimer’s Disease (AD) is a neurodegenerative disorder that is still not fully understood.
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
Sex modifies AD vulnerability, but the reasons for this are largely unknown. We utilize two …
PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model
BS Glicksberg, B Oskotsky, PM Thangaraj… - …, 2019 - academic.oup.com
Motivation Electronic health records (EHRs) are quickly becoming omnipresent in healthcare,
but interoperability issues and technical demands limit their use for biomedical and clinical …
but interoperability issues and technical demands limit their use for biomedical and clinical …
[PDF][PDF] A certified de-identification system for all clinical text documents for information extraction at scale
…, G Schenk, K Muenzen, B Oskotsky… - JAMIA …, 2023 - academic.oup.com
Objectives Clinical notes are a veritable treasure trove of information on a patient’s disease
progression, medical history, and treatment plans, yet are locked in secured databases …
progression, medical history, and treatment plans, yet are locked in secured databases …
A biomedical open knowledge network harnesses the power of AI to understand deep human biology
Abstract Knowledge representation and reasoning (KR&R) has been successfully implemented
in many fields to enable computers to solve complex problems with AI methods. However…
in many fields to enable computers to solve complex problems with AI methods. However…
Comparing ethnicity-specific reference intervals for clinical laboratory tests from EHR data
N Rappoport, H Paik, B Oskotsky, R Tor… - The journal of …, 2018 - academic.oup.com
Background The results of clinical laboratory tests are an essential component of medical
decision-making. To guide interpretation, test results are returned with reference intervals …
decision-making. To guide interpretation, test results are returned with reference intervals …