User profiles for Borries Demeler
Borries DemelerUniversity of Lethbridge Verified email at uleth.ca Cited by 10983 |
Analytical ultracentrifugation of complex macromolecular systems
An analytical ultracentrifuge is capable of directly measur-ing the sedimentationcoefficient, s,
the diffusion coefficient, D, and the molecular mass, M, of macromolecules ranging in size …
the diffusion coefficient, D, and the molecular mass, M, of macromolecules ranging in size …
[HTML][HTML] The open AUC project
Progress in analytical ultracentrifugation (AUC) has been hindered by obstructions to hardware
innovation and by software incompatibility. In this paper, we announce and outline the …
innovation and by software incompatibility. In this paper, we announce and outline the …
[HTML][HTML] Structural bases of unphosphorylated STAT1 association and receptor binding
…, MA Pastorello, W Wang, JS McMurray, B Demeler… - Molecular cell, 2005 - cell.com
The crystal structure has been determined at 3.0 Å resolution for an unphosphorylated
STAT1 (1–683) complexed with a phosphopeptide derived from the α chain of interferon γ (IFNγ) …
STAT1 (1–683) complexed with a phosphopeptide derived from the α chain of interferon γ (IFNγ) …
UltraScan: a comprehensive data analysis software package for analytical ultracentrifugation experiments
B Demeler - Modern analytical ultracentrifugation: techniques …, 2005 - books.google.com
With the introduction of the Beckman XL-I/A in the early 1990s, digital data acquisition from
the analytical ultracentrifuge has made it possible to readily analyze sedimentation data with …
the analytical ultracentrifuge has made it possible to readily analyze sedimentation data with …
Multi-wavelength analytical ultracentrifugation of biopolymer mixtures and interactions
Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made
possible by new analytical ultracentrifuge optical systems. MW-AUC extends the basic …
possible by new analytical ultracentrifuge optical systems. MW-AUC extends the basic …
Sedimentation velocity analysis of highly heterogeneous systems
B Demeler, KE Van Holde - Analytical biochemistry, 2004 - Elsevier
This article discusses several improvements to the van Holde–Weischet (vHW) method [Biopolymers
17 (1978) 1387] that address its capability to deal with sedimentation coefficient …
17 (1978) 1387] that address its capability to deal with sedimentation coefficient …
A two-dimensional spectrum analysis for sedimentation velocity experiments of mixtures with heterogeneity in molecular weight and shape
We report a model-independent analysis approach for fitting sedimentation velocity data which
permits simultaneous determination of shape and molecular weight distributions for mono…
permits simultaneous determination of shape and molecular weight distributions for mono…
[HTML][HTML] Structure of the Hsp110: Hsc70 nucleotide exchange machine
Hsp70s mediate protein folding, translocation, and macromolecular complex remodeling
reactions. Their activities are regulated by proteins that exchange ADP for ATP from the …
reactions. Their activities are regulated by proteins that exchange ADP for ATP from the …
Structural basis of HIV-1 capsid recognition by PF74 and CPSF6
Upon infection of susceptible cells by HIV-1, the conical capsid formed by ∼250 hexamers
and 12 pentamers of the CA protein is delivered to the cytoplasm. The capsid shields the …
and 12 pentamers of the CA protein is delivered to the cytoplasm. The capsid shields the …
[HTML][HTML] Dissociation of human copper-zinc superoxide dismutase dimers using chaotrope and reductant: Insights into the molecular basis for dimer stability
…, LJ Whitson, X Cao, V Schirf, B Demeler… - Journal of Biological …, 2004 - ASBMB
The dissociation of apo- and metal-bound human copper-zinc superoxide dismutase (SOD1)
dimers induced by the chaotrope guanidine hydrochloride (GdnHCl) or the reductant Tris(2-…
dimers induced by the chaotrope guanidine hydrochloride (GdnHCl) or the reductant Tris(2-…