User profiles for Boxi Kang
Boxi KangPeking University Verified email at pku.edu.cn Cited by 14876 |
[HTML][HTML] Understanding tumor ecosystems by single-cell sequencing: promises and limitations
Cellular heterogeneity within and across tumors has been a major obstacle in understanding
and treating cancer, and the complex heterogeneity is masked if bulk tumor tissues are …
and treating cancer, and the complex heterogeneity is masked if bulk tumor tissues are …
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
Tremendous amount of RNA sequencing data have been produced by large consortium
projects such as TCGA and GTEx, creating new opportunities for data mining and deeper …
projects such as TCGA and GTEx, creating new opportunities for data mining and deeper …
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
Introduced in 2017, the GEPIA (Gene Expression Profiling Interactive Analysis) web server
has been a valuable and highly cited resource for gene expression analysis based on tumor …
has been a valuable and highly cited resource for gene expression analysis based on tumor …
[PDF][PDF] Landscape of infiltrating T cells in liver cancer revealed by single-cell sequencing
Systematic interrogation of tumor-infiltrating lymphocytes is key to the development of
immunotherapies and the prediction of their clinical responses in cancers. Here, we perform deep …
immunotherapies and the prediction of their clinical responses in cancers. Here, we perform deep …
Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
Cancer immunotherapies have shown sustained clinical responses in treating non-small-cell
lung cancer 1 , 2 – 3 , but efficacy varies and depends in part on the amount and properties …
lung cancer 1 , 2 – 3 , but efficacy varies and depends in part on the amount and properties …
Lineage tracking reveals dynamic relationships of T cells in colorectal cancer
T cells are key elements of cancer immunotherapy 1 but certain fundamental properties,
such as the development and migration of T cells within tumours, remain unknown. The …
such as the development and migration of T cells within tumours, remain unknown. The …
Stress–glucocorticoid–TSC22D3 axis compromises therapy-induced antitumor immunity
Psychological distress has long been suspected to influence cancer incidence and mortality.
It remains largely unknown whether and how stress affects the efficacy of anticancer …
It remains largely unknown whether and how stress affects the efficacy of anticancer …
[HTML][HTML] SciBet as a portable and fast single cell type identifier
Fast, robust and technology-independent computational methods are needed for supervised
cell type annotation of single-cell RNA sequencing data. We present SciBet, a supervised …
cell type annotation of single-cell RNA sequencing data. We present SciBet, a supervised …
[HTML][HTML] Distinct epigenetic features of tumor-reactive CD8+ T cells in colorectal cancer patients revealed by genome-wide DNA methylation analysis
Background Tumor-reactive CD8+ tumor-infiltrating lymphocytes (TILs) represent a subtype
of T cells that can recognize and destroy tumor specifically. Understanding the regulatory …
of T cells that can recognize and destroy tumor specifically. Understanding the regulatory …
[HTML][HTML] Cellular basis of enhanced humoral immunity to SARS-CoV-2 upon homologous or heterologous booster vaccination analyzed by single-cell immune …
…, Z He, A Cui, Y Zhou, J Wu, M Zhou, G Yuan, B Kang… - Cell Discovery, 2022 - nature.com
SARS-CoV-2 vaccine booster dose can induce a robust humoral immune response, however,
its cellular mechanisms remain elusive. Here, we investigated the durability of antibody …
its cellular mechanisms remain elusive. Here, we investigated the durability of antibody …