User profiles for Bradley J. Main

Bradley J. Main

UC Davis
Verified email at ucdavis.edu
Cited by 1927

[HTML][HTML] An amplicon-based sequencing framework for accurately measuring intrahost virus diversity using PrimalSeq and iVar

…, J Quick, NL Matteson, JG De Jesus, BJ Main… - Genome biology, 2019 - Springer
How viruses evolve within hosts can dictate infection outcomes; however, reconstructing
this process is challenging. We evaluate our multiplexed amplicon approach, PrimalSeq, to …

Adaptive introgression in an African malaria mosquito coincident with the increased usage of insecticide-treated bed nets

LC Norris, BJ Main, Y Lee, TC Collier… - Proceedings of the …, 2015 - National Acad Sciences
Animal species adapt to changes in their environment, including man-made changes such
as the introduction of insecticides, through selection for advantageous genes already present …

[HTML][HTML] Impact of temperature on the extrinsic incubation period of Zika virus in Aedes aegypti

OC Winokur, BJ Main, J Nicholson… - PLoS neglected tropical …, 2020 - journals.plos.org
Since Zika virus (ZIKV) emerged as a global human health threat, numerous studies have
pointed to Aedes aegypti as the primary vector due to its high competence and propensity to …

Spatiotemporal dynamics of gene flow and hybrid fitness between the M and S forms of the malaria mosquito, Anopheles gambiae

…, LC Norris, TC Collier, BJ Main… - Proceedings of the …, 2013 - National Acad Sciences
The M and S forms of Anopheles gambiae have been the focus of intense study by malaria
researchers and evolutionary biologists interested in ecological speciation. Divergence …

[HTML][HTML] The Genetic Basis of Host Preference and Resting Behavior in the Major African Malaria Vector, Anopheles arabiensis

BJ Main, Y Lee, HM Ferguson, KS Kreppel… - PLoS …, 2016 - journals.plos.org
Malaria transmission is dependent on the propensity of Anopheles mosquitoes to bite humans
(anthropophily) instead of other dead end hosts. Recent increases in the usage of Long …

Regulatory Divergence in Drosophila melanogaster and D. simulans, a Genomewide Analysis of Allele-Specific Expression

RM Graze, LM McIntyre, BJ Main, ML Wayne… - Genetics, 2009 - academic.oup.com
Species-specific regulation of gene expression contributes to the development and maintenance
of reproductive isolation and to species differences in ecologically important traits. A …

[HTML][HTML] Vector competence of Aedes aegypti, Culex tarsalis, and Culex quinquefasciatus from California for Zika virus

BJ Main, J Nicholson, OC Winokur… - PLoS neglected …, 2018 - journals.plos.org
Zika virus (ZIKV) has emerged since 2013 as a significant global human health threat following
outbreaks in the Pacific Islands and rapid spread throughout South and Central America. …

[HTML][HTML] Allele-specific expression assays using Solexa

BJ Main, RD Bickel, LM McIntyre, RM Graze… - BMC genomics, 2009 - Springer
Background Allele-specific expression (ASE) assays can be used to identify cis, trans, and
cis-by-trans regulatory variation. Understanding the source of expression variation has …

TNF‐mediated inflammatory disease

JR Bradley - The Journal of Pathology: A Journal of the …, 2008 - Wiley Online Library
TNF was originally described as a circulating factor that can cause necrosis of tumours, but
has since been identified as a key regulator of the inflammatory response. This review …

[HTML][HTML] Evidence for physical therapies (airway clearance and physical training) in cystic fibrosis: an overview of five Cochrane systematic reviews

JM Bradley, FM Moran, JS Elborn - Respiratory medicine, 2006 - Elsevier
… The aim of this paper is to summarise the main findings from Cochrane systematic reviews
… The aim of this paper is to summarise the main findings of Cochrane systematic reviews that …