Numerous synthetic biology endeavors require well-tuned co-expression of functional
components for success. Classically, monodirectional promoters (MDPs) have been used for such …

One primary objective of synthetic biology is to improve the sustainability of chemical
manufacturing. Naturally occurring biological systems can utilize a variety of carbon sources, …

One major challenge in synthetic biology is the deleterious impacts of cellular stress caused
by expression of heterologous pathways, sensors, and circuits. Feedback control and …

Utilization of lignin, an abundant renewable resource, is limited by its heterogenous
composition and complex structure. Biological valorization of lignin provides advantages over …

The industrial biotechnology sector—commercial-scale manufacturing of chemical products
by use of cellular or molecular biocatalysts—lies at a crossroads. Metabolic engineering …

Advancements in synthetic biology have provided new opportunities in biosensing, with
applications ranging from genetic programming to diagnostics. Next generation biosensors aim …

Ultra-sensitive, label-free biosensors have the potential to have a tremendous impact on
fields like medical diagnostics. For the majority of these Si-based integrated devices, it is …

Achieving sustainable chemical synthesis and a circular economy will require process
innovation to minimize or recover existing waste streams. Valorization of lignin biomass has the …

Dynamic pathway regulation has emerged as a promising strategy in metabolic engineering
for improved system productivity and yield, and continues to grow in sophistication. …

Recent advances in metabolic engineering have demonstrated the potential to exploit
biological chemistry for the synthesis of complex molecules. Much of the progress to date has …