Unlocking de novo antibody design with generative artificial intelligence

…, G Rakocevic, JM Gutierrez, C Chung, BK Luton… - bioRxiv, 2023 - biorxiv.org
Generative artificial intelligence (AI) has the potential to greatly increase the speed, quality
and controllability of antibody design. Traditional de novo antibody discovery requires time …

Positron Emission Tomography Tracer Design of Targeted Synthetic Peptides via 18F-Sydnone Alkyne Cycloaddition

…, NA LaBerge, M Nason, AL Cantu, BK Luton… - Bioconjugate …, 2021 - ACS Publications
Chemically synthesized, small peptides that bind with high affinity and specificity to CD8-expressing
(CD8+) tumor-infiltrating T cells, yet retain the desirable characteristics of small …

In vitro validated antibody design against multiple therapeutic antigens using generative inverse folding

…, S Levine, JA Khan, C Chung, N Diaz, BK Luton… - bioRxiv, 2023 - biorxiv.org
Deep learning approaches have demonstrated the ability to design protein sequences given
backbone structures [1, 2, 3, 4, 5]. While these approaches have been applied in silico to …

validated antibody design against multiple therapeutic antigens using generative inverse folding

A Shanehsazzadeh - NeurIPS 2023 Generative AI and Biology …, 2023 - openreview.net
… We define a protein graph as a directed graph where residues are represented as nodes
and share edges with their k nearest neighbors. We use k = 48 in all of our experiments. We …

[PDF][PDF] Sam Houston State University Alma Mater

BOF REGENTS - shsu.edu
A native of Jacksonville, TX, Ms. Jackson attended Sam Houston State University after high
school, double majoring in Journalism and Political Science. During her time as a student, Ms…

[HTML][HTML] Speaking the Same Language? Translation between Languages and Translation in Science

MK Boettger, J House - Contrastive Pragmatics, 2023 - brill.com
Translational science describes a process of transferring basic science into applied science.
While it carries the term “translation” in its name, the original concept of translation refers to …

Using AI to design antibodies

G Rakočević - 4th Belgrade Bioinformatics Conference, 2023 - imagine.imgge.bg.ac.rs
Advancements in antibody engineering are crucial for developing effective and safe therapeutic
candidates. Traditional approaches often involve limited screening of sequence space, …

[BOOK][B] Race, gender, and citizenship in the African diaspora: travelling blackness

M Celeste - 2016 - taylorfrancis.com
Winner of the National Communication Association's 2018 Diamond Anniversary Book Award
With the exception of slave narratives, there are few stories of black international migration …

Multilevel regression modelling of melanoma incidence

AC Brown - 2007 - uobrep.openrepository.com
This thesis is concerned with developing and implementing a method for modelling and
projecting cancer incidence data. The burden of cancer is an increasing problem for society and …

Physiological and psychological impacts of nighttime call response in firefighters from volunteer and paid-on-call fire departments

LA Wolski, JR Gawryluk - 2019 - dspace.library.uvic.ca
… Last but certainly not least, the biggest thank-you to my fiancé, Breanna. You’ve put up with
nights of me waking you up to attend a call for data collection without complaint, have been …