The Hippo pathway and its regulatory target, YAP, has recently emerged as an important
biochemical signaling pathway that tightly governs epithelial tissue growth. Initially defined in …

… (H) Dot plots of Col1A1 and Timp1 expression by real‐time quantitative RT‐PCR from
YAP‐Tg and Yap‐Tg/sgCyr61 whole livers at 2 weeks after TetOYAP induction. *P < 0.05, **P …

The Hippo pathway and its nuclear effector Yap regulate organ size and cancer formation.
While many modulators of Hippo activity have been identified, little is known about the Yap …

The Hippo pathway controls cell proliferation and differentiation through the precisely tuned
activity of a core kinase cassette. The activity of Hippo kinase is modulated by interactions …

Activated hepatocytes are hypothesized to be a major source of signals that drive cirrhosis,
but the biochemical pathways that convert hepatocytes into such a state are unclear. We …

BACKGROUND Little is known of how frailty, a dynamic measure of physiological age,
progresses relative to age or disability status. Operative treatment of adult spinal deformity (ASD) …

Hospital-acquired conditions (HACs) have been the focus of recent initiatives by the Centers
for Medicare and Medicaid Services in an effort to improve patient safety and outcomes. …

The Hippo pathway is a highly conserved signaling pathway responsible for the regulation of
cellular growth, proliferation and apoptosis. The Drosophila pathway is made up of four key …

The effects of bariatric surgery on diminishing spinal diagnoses have yet to be elucidated in
the literature. The purpose of this study was to assess the rate in which various spinal …

Adult cervical deformity is a structural malalignment of the cervical spine that may present with
variety of significant symptomatology for patients. There are clear and substantial negative …