Astrocytes become reactive in response to insults to the central nervous system by adopting
context-specific cellular signatures and outputs, but a systematic understanding of the …

Historical developments of cinema technology have contributed to the apparent reality of
movie-goers’ experience. The current study uses both self-report and physiological measures (…

Background The phase 3 SPARTAN study evaluated apalutamide versus placebo in
patients with nonmetastatic castration-resistant prostate cancer (nmCRPC) and prostate-specific …

There is an abundance of literature highlighting the need to focus on enhancing students’
creativity in higher education. However, currently there is a gap in awareness of evidence-…

Background The proteasome inhibitor bortezomib was initially approved for the treatment of
relapsed mantle-cell lymphoma. We investigated whether substituting bortezomib for …

The Riemann Hypothesis has become the Holy Grail of mathematics in the century and a half
since 1859 when Bernhard Riemann, one of the extraordinary mathematical talents of the …

Media-saturated digital environments seek to influence social media users’ behaviour,
including through marketing. The World Health Organization has identified food marketing, …

Background The topic of food is broad and global, thereby representing an influential sector
of the economy. Motivated by the advent of Industry 4.0, massive potential exists to …

Cellular perturbations underlying Alzheimer's disease (AD) are primarily studied in human
postmortem samples and model organisms. Here, we generated a single-nucleus atlas from a …

Advancing from gene discovery in autism spectrum disorders (ASDs) to the identification of
biologically relevant mechanisms remains a central challenge. Here, we perform parallel in …