JWS Online is a repository of kinetic models, describing biological systems, which can be
interactively run and interrogated over the Internet. It is implemented using a client–server …

To the Editor—Reconstructing metabolic reaction networks enables the development of
testable hypotheses of an organism’s metabolism under different conditions 1. State-of-the-art …

Abstract Systems biology has experienced dramatic growth in the number, size, and
complexity of computational models. To reproduce simulation results and reuse models, …

A central focus in studies of microbial communities is the elucidation of the relationships
between genotype, phenotype, and dynamic community structure. Here, we present a new …

The Python Simulator for Cellular Systems (PySCeS) is an extendable research tool for the
numerical analysis and investigation of cellular systems. Availability: PySCeS is distributed …

Background Several genome-scale metabolic reconstruction software platforms have been
developed and are being continuously updated. These tools have been widely applied to …

Background With the ever increasing use of computational models in the biosciences, the
need to share models and reproduce the results of published studies efficiently and easily is …

Computational models can help researchers to interpret data, understand biological functions,
and make quantitative predictions. The Systems Biology Markup Language (SBML) is a …

Systems Biology aims to understand quantitatively how properties of biological systems can
be understood as functions of the characteristics of, and interactions between their …

Microbial communities are ubiquitously found in Nature and have direct implications for the
environment, human health and biotechnology. The species composition and overall …