[HTML][HTML] WDR23 regulates NRF2 independently of KEAP1

JY Lo, BN Spatola, SP Curran - PLoS Genetics, 2017 - journals.plos.org
Cellular adaptation to stress is essential to ensure organismal survival. NRF2/NFE2L2 is a
key determinant of xenobiotic stress responses, and loss of negative regulation by the KEAP1-…

[HTML][HTML] Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates

BN Spatola, JY Lo, B Wang, SP Curran - Scientific Reports, 2019 - nature.com
Maintaining a healthy cellular environment requires the constant control of proteostasis. E3
ubiquitin ligase complexes facilitate the post-translational addition of ubiquitin, which based …

Hepatic WDR23 proteostasis mediates insulin clearance by regulating insulin-degrading enzyme

C Duangjan, TE Arpawong, BN Spatola, SP Curran - BioRxiv, 2022 - biorxiv.org
Clearance of circulating insulin is critical for metabolic homeostasis. In the liver, insulin is
degraded by the activity of the insulin-degrading enzyme (IDE). Here we establish a hepatic …

Development of microsatellite loci for the western slimy salamander (Plethodon albagula) using 454 sequencing

BN Spatola, WE Peterman, NT Stephens… - Conservation Genetics …, 2013 - Springer
Terrestrial salamanders of the genus Plethodon are closely tied to abiotic environmental
habitat features and are particularly sensitive to land use and habitat change. To better …

Identification of Polymorphic Loci in Ambystoma annulatum and Review of Cross-species Microsatellite Use in the Genus Ambystoma

WE Peterman, GM Connette, BN Spatola… - Copeia, 2012 - meridian.allenpress.com
We screened 74 published microsatellite primers in Ambystoma annulatum, a species for
which no microsatellite markers have been developed. Overall, we had a moderate success …

[HTML][HTML] Precuneus brain response changes differently during human–robot and human–human dyadic social interaction

N Spatola, T Chaminade - Scientific Reports, 2022 - nature.com
Human–human interactions (HHI) and human–robot interactions (HRI) are compared to
identify differences between cognitive processes reflecting bonding in social interactions with …

Cognitive impact of anthropomorphized robot gaze: Anthropomorphic gaze as social cues

N Spatola, P Huguet - ACM Transactions on Human-Robot Interaction …, 2021 - dl.acm.org
… ” to PH, and a post-doctoral grant to NS Authors’ addresses: N. Spatola, Istituto Italiano di
Tecnologia, Social Cognition in Human-Robot Interaction, 16152 Genova, Italy; email: Nicolas.…

[HTML][HTML] Perceived facial happiness during conversation correlates with insular and hypothalamus activity for humans, not robots

T Chaminade, N Spatola - Frontiers in Psychology, 2022 - frontiersin.org
Emotional contagion, in particular of happiness, is essential to creating social bonds. The
somatic marker hypothesis posits that embodied physiological changes associated with …

Robot humanization measure/task

N Spatola, S Marchesi, A Wykowska - 2021 - psyarxiv.com
In human-robot interaction, one key factor to predict and understand how human engage
and interact with robots is how the inter-individual differences in how they perceive, consider …

Cdc48/Shp1 participates in dissociation of protein complexes to regulate their activity

L Lauinger, K Flick, P Kaiser - Current Genetics, 2021 - Springer
The AAA-ATPase p97/Cdc48 is one of the most abundant proteins in eukaryotes, and owing
to its multiple functions, is considered the swiss army knife of cells. Recent findings …