User profiles for Brian M. Zid
Brian ZidUC San Diego Verified email at ucsd.edu Cited by 3053 |
[PDF][PDF] Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
In many species, reducing nutrient intake without causing malnutrition extends lifespan [1–3].
Like DR (dietary restriction), modulation of genes in the insulin-signaling pathway, known …
Like DR (dietary restriction), modulation of genes in the insulin-signaling pathway, known …
[HTML][HTML] 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
Dietary restriction (DR) extends lifespan in multiple species. To examine the mechanisms of
lifespan extension upon DR, we assayed genome-wide translational changes in Drosophila. …
lifespan extension upon DR, we assayed genome-wide translational changes in Drosophila. …
Promoter sequences direct cytoplasmic localization and translation of mRNAs during starvation in yeast
BM Zid, EK O'Shea - Nature, 2014 - nature.com
A universal feature of the response to stress and nutrient limitation is transcriptional upregulation
of genes that encode proteins important for survival. Under many such conditions, the …
of genes that encode proteins important for survival. Under many such conditions, the …
[PDF][PDF] An integrated approach reveals regulatory controls on bacterial translation elongation
AR Subramaniam, BM Zid, EK O'Shea - Cell, 2014 - cell.com
Ribosomes elongate at a nonuniform rate during translation. Theoretical models and
experiments disagree on the in vivo determinants of elongation rate and the mechanism by which …
experiments disagree on the in vivo determinants of elongation rate and the mechanism by which …
Stress‐induced mRNP granules: form and function of processing bodies and stress granules
… The authors would like to thank the Zid lab for helpful discussions on this review. Research
on mRNP granules in the Zid lab is supported by grant R35 GM128798 from the National …
on mRNP granules in the Zid lab is supported by grant R35 GM128798 from the National …
Water-and nutrient-dependent effects of dietary restriction on Drosophila lifespan
Dietary restriction (DR) is a widely conserved intervention leading to lifespan extension.
Despite considerable effort, the mechanisms underlying DR remain poorly understood. In …
Despite considerable effort, the mechanisms underlying DR remain poorly understood. In …
Mitochondrial volume fraction and translation duration impact mitochondrial mRNA localization and protein synthesis
… We thank members of the Zid laboratory as well as T Endo, S Iwasaki, G Goshima, E …
We thank M Zid, A Guzikowski and V Harjono for critically reading the manuscript. This work …
We thank M Zid, A Guzikowski and V Harjono for critically reading the manuscript. This work …
Quantification of elongation stalls and impact on gene expression in yeast
…, V Harjono, AT Harvey, AR Subramaniam, BM Zid - RNA, 2023 - rnajournal.cshlp.org
Ribosomal pauses are a critical part of cotranslational events including protein folding and
localization. However, extended ribosome pauses can lead to ribosome collisions, resulting …
localization. However, extended ribosome pauses can lead to ribosome collisions, resulting …
[HTML][HTML] DDX3 suppresses type I interferons and favors viral replication during Arenavirus infection
Several arenaviruses cause hemorrhagic fever (HF) diseases that are associated with high
morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-…
morbidity and mortality in humans. Accordingly, HF arenaviruses have been listed as top-…
[HTML][HTML] Mitochondrial mRNA localization is governed by translation kinetics and spatial transport
For many nuclear-encoded mitochondrial genes, mRNA localizes to the mitochondrial
surface co-translationally, aided by the association of a mitochondrial targeting sequence (MTS) …
surface co-translationally, aided by the association of a mitochondrial targeting sequence (MTS) …