Unique spatiotemporal activation pattern of Cdc42 by Gef1 and Scd1 promotes different events during cytokinesis

B Wei, BS Hercyk, N Mattson… - Molecular biology of …, 2016 - Am Soc Cell Biol
The Rho-family GTPase Cdc42 regulates cell polarity and localizes to the cell division site.
Cdc42 is activated by guanine nucleotide exchange factors (GEFs). We report that Cdc42 …

Coordinating septum formation and the actomyosin ring during cytokinesis in Schizosaccharomyces pombe

BS Hercyk, UN Onwubiko, ME Das - Molecular microbiology, 2019 - Wiley Online Library
During cytokinesis, animal and fungal cells form a membrane furrow via actomyosin ring
constriction. Our understanding of actomyosin ring‐driven cytokinesis stems extensively from …

A novel interplay between GEFs orchestrates Cdc42 activity during cell polarity and cytokinesis in fission yeast

BS Hercyk, J Rich-Robinson, AS Mitoubsi… - Journal of cell …, 2019 - journals.biologists.com
Cdc42, a conserved regulator of cell polarity, is activated by two GEFs, Gef1 and Scd1, in
fission yeast. Why the cell needs two GEFs is unclear, given that they are partially redundant …

Cdc42 GTPase activating proteins Rga4 and Rga6 coordinate septum synthesis and membrane trafficking at the division plane during cytokinesis

BF Campbell, BS Hercyk, AR Williams, E San Miguel… - Traffic, 2022 - Wiley Online Library
Fission yeast cytokinesis is driven by simultaneous septum synthesis, membrane furrowing
and actomyosin ring constriction. The septum consists of a primary septum flanked by …

F-BAR Cdc15 Promotes Cdc42 Activation During Cytokinesis and Cell Polarization in Schizosaccharomyces pombe

BS Hercyk, ME Das - Genetics, 2019 - academic.oup.com
Cdc42, a Rho-family GTPase, is a master regulator of cell polarity. Recently, it has been
shown that Cdc42 also facilitates proper cytokinesis in the fission yeast Schizosaccharomyces …

The role for CYCLIN A1; 2/TARDY ASYNCHRONOUS MEIOSIS in differentiated cells in Arabidopsis

AK Jha, Y Wang, BS Hercyk, HS Shin, R Chen… - Plant molecular …, 2014 - Springer
The Arabidopsis A1-type cyclin, CYCA1;2, also named TARDY ASYNCHRONOUS MEIOSIS
(TAM), is known for its positive role in meiotic cell cycle progression, but its function in other …

Spatiotemporal analysis of cytokinetic events in fission yeast

B Wei, BS Hercyk, J Habiyaremye, M Das - JoVE (Journal of Visualized …, 2017 - jove.com
Cytokinesis, the final step in cell division is critical for maintaining genome integrity. Proper
cytokinesis is important for cell differentiation and development. Cytokinesis involves a series …

[PDF][PDF] F-BAR Cdc15 Promotes Gef1-mediated Cdc42 Activation During Cytokinesis and Cell Polarization in S. pombe 2

BS Hercyk, ME Das - scholar.archive.org
… known about how Cdc42 promotes actin organization and polarization, 52 the
spatiotemporal manner in which regulation of Cdc42 is fine-tuned is not well 53 understood. …

[PDF][PDF] Ajay K. Jha, Yixing Wang, Brian S. Hercyk, Hwa-Soo Shin, Rujin Chen &

M Yang - Plant Mol Biol, 2014 - researchgate.net
Accepted: 24 December 2013/Published online: 16 January 2014© Springer Science+
Business Media Dordrecht 2014 the transgene transcript levels were approximately 72-and 45-…

CELL MORPHOLOGY AND CELL DIVISION ARE PRECISELY CONTROLLED THOUGH DIFFERENTIAL REGULATION OF CDC42

B Hercyk - 2019 - trace.tennessee.edu
… A version of this chapter was originally published by Brian Hercyk and Maitreyi Das: Hercyk
… Author contributions: this manuscript was written by Brian Hercyk and edited by Maitreyi Das…