MORC2 encodes an ATPase that plays a role in chromatin remodeling, DNA repair, and
transcriptional regulation. Heterozygous variants in MORC2 have been reported in individuals …

Evolutionary expansion of the human neocortex is partially attributed to a relative abundance
of neural stem cells in the fetal brain called outer radial glia (oRG). oRG cells display a …

Meningitis and encephalitis are leading causes of central nervous system (CNS) disease and
often result in severe neurological compromise or death. Traditional diagnostic workflows …

Background and Objectives Patients with multiple sclerosis (MS) may seek fertility treatment
(FT)—including in vitro fertilization (IVF). Variable relapse risk after IVF has been reported in …

Highlights • Description of the neural stem and progenitor cells of the developing human
neocortex, specifically the origins and current knowledge regarding outer radial glia. • …

The development of the central nervous system can be directly disrupted by a variety of
acquired factors, including infectious, inflammatory, hypoxic-ischemic, and toxic insults. …

Background The effects of pregnancy on multiple sclerosis (MS) inflammatory activity are
not well described in women with moderate to severe disabilities. Objective To quantify the …

… The authors declare the following financial interests/personal relationships which may be
considered as potential competing interests: Bridget Ostrem reports financial support was …

Background Preterm white matter injury (PWMI) is the most common cause of brain injury in
premature neonates. PWMI involves a differentiation arrest of oligodendrocytes, the …

In utero infection and maternal inflammation can adversely impact fetal brain development.
Maternal systemic illness, even in the absence of direct fetal central nervous system infection, …