O‐Glc NA cylation is an essential, nutrient‐sensitive post‐translational modification, but its
biochemical and phenotypic effects remain incompletely understood. To address this question…

Protein secretion is an essential process that drives cell growth, movement, and communication.
Protein traffic within the secretory pathway occurs via transport intermediates that bud …

The COPII coat complex, which mediates secretory cargo trafficking from the endoplasmic
reticulum, is a key control point for subcellular protein targeting. Because misdirected proteins …

The coat protein complex II (COPII) mediates forward trafficking of protein and lipid cargoes
from the endoplasmic reticulum. COPII is an ancient and essential pathway in all eukaryotes …

O-linked β-N-acetylglucosamine (O-GlcNAc) is a dynamic form of intracellular glycosylation
common in animals, plants and other organisms. O-GlcNAcylation is essential in mammalian …

O-linked β-N-acetylglucosamine (O-GlcNAc) is an abundant and essential intracellular form
of protein glycosylation in animals and plants. In humans, dysregulation of O-GlcNAcylation …

Gigaxonin (also known as KLHL16) is an E3 ligase adaptor protein that promotes the
ubiquitination and degradation of intermediate filament (IF) proteins. Mutations in human gigaxonin …

Trehalose is a disaccharide produced by many organisms to better enable them to survive
environmental stresses, including heat, cold, desiccation, and reactive oxygen species. …

Coat protein complex II (COPII) mediates forward vesicle trafficking from the endoplasmic
reticulum (ER). As an evolutionarily conserved system, COPII is essential for maintaining the …

Background: Vasoactive intestinal peptide (VIP) is a 3.3 kDa pleiotropic protein with a broad
expression profile that displays immune modulating activities. VIP binds two G protein-…