Renewed interest in malaria eradication has placed greater emphasis on the development
of tools to interrupt Plasmodium transmission, such as transmission-blocking vaccines. …

A mosquito needs to ingest at least one male and one female gametocyte to become
infected with malaria. The sex of Plasmodium falciparum gametocytes can be determined …

Recent progress in GBS vaccine research holds promise of reducing the large and
preventable burden of mortality and disability caused by GBS disease, especially in higher-burden …

Background Group B streptococcus (GBS) colonisation during pregnancy can lead to invasive
GBS disease (iGBS) in infants, including meningitis or sepsis, with a high mortality risk. …

A detailed understanding of the human infectious reservoir is essential for improving
malaria transmission-reducing interventions. Here we report a multi-regional assessment of …

Background Plasmodium falciparum gametocytes are essential for malaria transmission.
Malaria control measures that aim at reducing transmission require an accurate …

Background Severe Plasmodium falciparum malaria is a major cause of death in children.
The contribution of the parasite burden to the pathogenesis of severe malaria has been …

Malaria infections occurring below the limit of detection of standard diagnostics are common
in all endemic settings. However, key questions remain surrounding their contribution to …

Background We describe demographic features, treatments and clinical outcomes in the
International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 …

Background Group B Streptococcus (GBS) disease is a leading cause of neonatal death, but
its long-term effects have not been studied after early childhood. The aim of this study was …