Background A standardized definition of post-hepatectomy haemorrhage (PHH) has not yet
been established. Methods An international study group of hepatobiliary surgeons from high-…

BACKGROUND: Posthepatectomy liver failure is a feared complication after hepatic resection
and a major cause of perioperative mortality. There is currently no standardized definition …

BACKGROUND: Despite the potentially severe impact of bile leakage on patients’
perioperative and long-term outcome, a commonly used definition of this complication after …

Acute pancreatitis (AP) is a common disease that normally runs a benign course in the
majority of patients. However in up to 20% of individuals the disease is severe and may be …

How evolutionary changes at enhancers affect the transcription of target genes remains an
important open question. Previous comparative studies of gene expression have largely …

Background Portal vein (PV) resection is used increasingly in pancreatic resections. There is
no agreed policy regarding anticoagulation. Methods A systematic review was performed to …

Background Accurate and simple prognostic criteria based on histopathology following
pancreaticoduodenectomy would be helpful in assessing prognosis and considering and …

Background Peptidylarginine deiminase enzymes (PADs) convert arginine residues to
citrulline in a process called citrullination or deimination. Recently, two PADs, PAD2 and PAD4, …

Background Since the Coronavirus disease-19(COVID-19) pandemic, the healthcare systems
are reallocating their medical resources, with consequent narrowed access to elective …

The RET tyrosine kinase signaling pathway is involved in the development of endocrine
resistant ER+ breast cancer. However, we know little about how ER+ cells activate RET …