A substantial fraction of the human genome is difficult to interrogate with short-read DNA
sequencing technologies due to paralogy, complex haplotype structures, or tandem repeats. …

The ocular surface, comprised of the transparent cornea, conjunctiva, and protective tear film,
forms a protective barrier defending deeper structures of the eye from particulate matter …

Silver nanoparticles (AgNPs) are a common antimicrobial additive for a variety of applications,
including wound care. However, AgNPs often undergo dissolution resulting in release of …

Ocular exposure to metal oxide engineered nanomaterials (ENMs) is common as exemplified
by zinc(II) oxide (ZnO), a major constituent of sunscreens and cosmetics. The ocular …

Background CRIPTO is a multi-functional signaling protein that promotes stemness and
oncogenesis. We previously developed a CRIPTO antagonist, ALK4 L75A -Fc, and showed that …

Purpose: Corneal keratocyte-fibroblast-myofibroblast (KFM) transformation plays a critical
role in corneal stromal wound healing. However, the impact of engineered nanomaterials (…

Graphene-based nanomaterials (GBNs) are widely used due to their chemical and physical
properties for multiple commercial and environmental applications. From an occupational …

Expression of CRIPTO, a factor involved in embryonic stem cells, fetal development, and
wound healing, is tied to poor prognosis in multiple cancers. Prior studies in triple negative …

Breast cancers are categorized into subtypes with distinctive therapeutic vulnerabilities based
on expression of clinically targetable receptors and other genes that mimic cell types of …

Expression of CRIPTO, a factor involved in embryonic stem cells, fetal development, and
wound healing, is tied to poor prognosis in multiple cancers. In previous models of triple …