User profiles for Bruce R Conklin
Bruce ConklinInvestigator Gladstone and Professor at UCSF Verified email at gladstone.ucsf.edu Cited by 27789 |
Integration of biological networks and gene expression data using Cytoscape
…, AR Pico, A Vailaya, PL Wang, A Adler, BR Conklin… - Nature protocols, 2007 - nature.com
Cytoscape is a free software package for visualizing, modeling and analyzing molecular and
genetic interaction networks. This protocol explains how to use Cytoscape to analyze the …
genetic interaction networks. This protocol explains how to use Cytoscape to analyze the …
GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
…, N Salomonis, K Vranizan, SC Lawlor, BR Conklin - Nature …, 2002 - nature.com
Fig. 1 Fatty-acid degradation pathway adapted from a view in GenMAPP. Each box represents
a gene. For the interactive output of this MAPP and other MAPPs from GenMAPP, see …
a gene. For the interactive output of this MAPP and other MAPPs from GenMAPP, see …
[HTML][HTML] MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data
…, KD Dahlquist, K Vranizan, SC Lawlor, BR Conklin - Genome biology, 2003 - Springer
MAPPFinder is a tool that creates a global gene-expression profile across all areas of biology
by integrating the annotations of the Gene Ontology (GO) Project with the free software …
by integrating the annotations of the Gene Ontology (GO) Project with the free software …
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
BR Conklin, Z Farfel, KD Lustig, D Julius, HR Bourne - Nature, 1993 - nature.com
AGONIST-BOUND receptors activate heterotrimeric (αβγ) G proteins by catalysing replacement
of GDP bound to the α-subunit by GTP 1–5 . Mutations in the C terminus of the α-subunit …
of GDP bound to the α-subunit by GTP 1–5 . Mutations in the C terminus of the α-subunit …
[HTML][HTML] WikiPathways: pathway editing for the people
… Contributed equally to this work with: Alexander R Pico, Thomas Kelder … Contributed
equally to this work with: Alexander R Pico, Thomas Kelder … We thank Susan Coort, Nathan …
equally to this work with: Alexander R Pico, Thomas Kelder … We thank Susan Coort, Nathan …
[PDF][PDF] MicroRNA regulation of cell lineages in mouse and human embryonic stem cells
Cell fate decisions of pluripotent embryonic stem (ES) cells are dictated by activation and
repression of lineage-specific genes. Numerous signaling and transcriptional networks …
repression of lineage-specific genes. Numerous signaling and transcriptional networks …
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
INTRODUCTION The human genome contains tens of thousands of loci that produce long
noncoding RNAs (lncRNAs), transcripts that have no apparent protein-coding potential. A …
noncoding RNAs (lncRNAs), transcripts that have no apparent protein-coding potential. A …
WikiPathways: building research communities on biological pathways
Here, we describe the development of WikiPathways ( http://www.wikipathways.org ), a public
wiki for pathway curation, since it was first published in 2008. New features are discussed, …
wiki for pathway curation, since it was first published in 2008. New features are discussed, …
Interfacing silicon nanowires with mammalian cells
W Kim, JK Ng, ME Kunitake, BR Conklin… - Journal of the American …, 2007 - ACS Publications
We present the first demonstration of a direct interface of silicon nanowires with mammalian
cells such as mouse embryonic stem (mES) cells and human embryonic kidney (HEK 293T) …
cells such as mouse embryonic stem (mES) cells and human embryonic kidney (HEK 293T) …
Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits
AD Federman, BR Conklin, KA Schrader, RR Reed… - Nature, 1992 - nature.com
AGONIST-BOUND receptors activate heterotrimeric (αβγ) G proteins by catalysing replacement
by GTP of GDP bound to the a subunit, resulting in dissociation of α-GTP from the βγ …
by GTP of GDP bound to the a subunit, resulting in dissociation of α-GTP from the βγ …