The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic
effect has also been postulated. Here, we demonstrate that changes in the …

The interrelationship between IgAs and microbiota diversity is still unclear. Here we show that
BALB/c mice had higher abundance and diversity of IgAs than C57BL/6 mice and that this …

Metagenomics is providing an unprecedented access to the environmental microbial diversity.
The amplicon-based metagenomics approach involves the PCR-targeted sequencing of a …

Alzheimer’s Disease (AD) is the most common cause of dementia affecting the elderly
population worldwide. We have performed a comprehensive transcriptome profiling of Late-Onset …

Lactobacillus rossiae is an obligately hetero-fermentative lactic acid bacterium, which can be
isolated from a broad range of environments including sourdoughs, vegetables, fermented …

The ATP-gated ionotropic P2X7 receptor regulates T follicular helper (Tfh) cell abundance in
the Peyer's patches (PPs) of the small intestine; deletion of P2rx7, encoding for P2X7, in Tfh …

Background Breast cancer (BC) is the most common malignancy in women, in whom it reaches
20% of the total neoplasia incidence. Most BCs are considered sporadic and a number …

The rapid expansion of multicellular native and alien species outbreaks in aquatic and
terrestrial ecosystems (bioinvasions) may produce significant impacts on bacterial community …

Background Substantial advances in microbiology, molecular evolution and biodiversity
have been carried out in recent years thanks to Metagenomics, which allows to unveil the …

Omenn syndrome (OS) is caused by hypomorphic Rag mutations and characterized by a
profound immunodeficiency associated with autoimmune-like manifestations. Both in humans …