User profiles for Bruno Maria Colombo
 | Bruno M ColomboUniversité d'Evry Paris-Saclay Verified email at univ-evry.fr Cited by 1253 |
[PDF][PDF] Inferring biologically relevant molecular tissue substructures by agglomerative clustering of digitized spatial transcriptomes with multilayer
J Moehlin, B Mollet, BM Colombo, MA Mendoza-Parra - Cell Systems, 2021 - cell.com
Spatially resolved transcriptomics (SrT) can investigate organ or tissue architecture from the
angle of gene programs that define their molecular complexity. However, computational …
angle of gene programs that define their molecular complexity. However, computational …
Biosensor-based enzyme engineering approach applied to psicose biosynthesis
…, A Cros, C Pophillat, BM Colombo… - Synthetic …, 2019 - academic.oup.com
Bioproduction of chemical compounds is of great interest for modern industries, as it reduces
their production costs and ecological impact. With the use of synthetic biology, metabolic …
their production costs and ecological impact. With the use of synthetic biology, metabolic …
PCNA and total nuclear protein content as markers of cell proliferation in pea tissue
…, S Sgorbati, M Levi, BM Colombo… - Journal of Cell …, 1992 - journals.biologists.com
The identification of cell proliferation markers has been shown to be a useful tool with which
to study basic mechanisms of cell cycle progression. The use of immunofluorescence …
to study basic mechanisms of cell cycle progression. The use of immunofluorescence …
Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs
…, A Bramoulle, M Lieb, BM Colombo… - Life Science …, 2023 - life-science-alliance.org
How cells respond to different external cues to develop along defined cell lineages to form
complex tissues is a major question in systems biology. Here, we investigated the potential of …
complex tissues is a major question in systems biology. Here, we investigated the potential of …
[HTML][HTML] A core transcription regulatory circuitry defining microglia cell identity inferred from the reanalysis of multiple human microglia differentiation protocols
Microglia, the immune cells in the brain involved in both homeostasis and injury/infection
control, play a predominant role in neurodegenerative diseases. In vivo studies on microglia …
control, play a predominant role in neurodegenerative diseases. In vivo studies on microglia …
PSEN1-M146V and PSEN1-A246E mutations associated with Alzheimers disease impair proper microglia differentiation
…, A Bramoulle, F Studer, BM Colombo… - bioRxiv, 2023 - biorxiv.org
Genetic variants associated with the late onset of Alzheimers disease (AD), were correlated
with genes known to be expressed in microglia, suggesting for an AD-genetic component …
with genes known to be expressed in microglia, suggesting for an AD-genetic component …
A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled programs
…, F Stüder, A Bramoulle, M Lieb, BM Colombo… - bioRxiv, 2022 - biorxiv.org
How cells respond to different external cues to develop along defined cell lineages to form
complex tissues is a major question in systems biology. Here, we investigated the potential of …
complex tissues is a major question in systems biology. Here, we investigated the potential of …
Application of peptidases from Maclura pomifera fruit for the production of active biopeptides from whey protein
A crude extract containing serine peptidases, was prepared from latex of Maclura pomifera
fruits. Peptidases were isolated by precipitation with one volume of ethanol with a yield of 5.4 …
fruits. Peptidases were isolated by precipitation with one volume of ethanol with a yield of 5.4 …
Inferring functionally relevant molecular tissue substructures by agglomerative clustering of digitized spatial transcriptomes
J Moehlin, B Mollet, BM Colombo, MA Mendoza-Parra - bioRxiv, 2020 - biorxiv.org
Developments on spatial transcriptomics (ST) are providing means to interrogate organ/tissue
architecture from the angle of the gene programs defining their molecular complexity. …
architecture from the angle of the gene programs defining their molecular complexity. …
Synergistic activation of RARb and RARg nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARa-controlled programs
…, F Stüder, A Bramoulle, M Lieb, BM Colombo… - 2022 - hal.science
How cells respond to different external cues to develop along defined cell lineages to form
complex tissues is a major question in systems biology. Here, we investigated the potential of …
complex tissues is a major question in systems biology. Here, we investigated the potential of …