User profiles for Bryan T. Grenfell

Bryan Grenfell

Kathryn Briger and Sarah Fenton Professor of Ecology and Public Affairs, Princeton …
Verified email at princeton.edu
Cited by 61569

Unifying the epidemiological and evolutionary dynamics of pathogens

BT Grenfell, OG Pybus, JR Gog, JLN Wood, JM Daly… - science, 2004 - science.org
A key priority for infectious disease research is to clarify how pathogen genetic variation,
modulated by host immunity, transmission bottlenecks, and epidemic dynamics, determines the …

Synchrony, waves, and spatial hierarchies in the spread of influenza

…, DL Smith, L Simonsen, MA Miller, BT Grenfell - science, 2006 - science.org
Quantifying long-range dissemination of infectious diseases is a key issue in their dynamics
and control. Here, we use influenza-related mortality data to analyze the between-state …

An investigation of transmission control measures during the first 50 days of the COVID-19 epidemic in China

…, P Zheng, Q Wang, ON Bjornstad, R Yang, BT Grenfell… - Science, 2020 - science.org
Responding to an outbreak of a novel coronavirus [agent of coronavirus disease 2019 (COVID-19)]
in December 2019, China banned travel to and from Wuhan city on 23 January 2020 …

Travelling waves and spatial hierarchies in measles epidemics

BT Grenfell, ON Bjørnstad, J Kappey - Nature, 2001 - nature.com
Spatio-temporal travelling waves are striking manifestations of predator–prey and host–parasite
dynamics. However, few systems are well enough documented both to detect repeated …

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

…, OG Pybus, AL Graham, SA Levin, BT Grenfell… - Science, 2021 - science.org
INTRODUCTION As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic continues, the deployment of safe and effective vaccines presents a key intervention …

Global trends in antimicrobial use in food animals

…, C Brower, M Gilbert, BT Grenfell… - Proceedings of the …, 2015 - National Acad Sciences
Demand for animal protein for human consumption is rising globally at an unprecedented
rate. Modern animal production practices are associated with regular use of antimicrobials, …

Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data

…, A Ashok, Q Caudron, BT Grenfell… - The Lancet infectious …, 2014 - thelancet.com
Background Antibiotic drug consumption is a major driver of antibiotic resistance. Variations
in antibiotic resistance across countries are attributable, in part, to different volumes and …

Age, sex, density, winter weather, and population crashes in Soay sheep

…, TH Clutton-Brock, MJ Crawley, BT Grenfell - Science, 2001 - science.org
Quantifying the impact of density, extrinsic climatic fluctuations, and demography on
population fluctuations is a persistent challenge in ecology. We analyzed the effect of these …

Dynamics of the 2001 UK foot and mouth epidemic: stochastic dispersal in a heterogeneous landscape

…, SJ Cornell, J Kappey, J Wilesmith, BT Grenfell - Science, 2001 - science.org
Foot-and-mouth is one of the world's most economically important livestock diseases. We
developed an individual farm–based stochastic model of the current UK epidemic. The fine …

Population dynamics of rapid fixation in cytotoxic T lymphocyte escape mutants of influenza A

…, ADME Osterhaus, BT Grenfell - Proceedings of the …, 2003 - National Acad Sciences
The dynamics of cellular immunity against pathogens, and its interaction with the human MHC
system, is a key area for empirical research, both within individual hosts and in population …