Complex microbial communities shape the dynamics of various environments, ranging from
the mammalian gastrointestinal tract to the soil. Advances in DNA sequencing technologies …

The ongoing COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) has resulted in more than 28,000,000 infections and 900,000 deaths …

Autism spectrum disorder (ASD) manifests as alterations in complex human behaviors including
social communication and stereotypies. In addition to genetic risks, the gut microbiome …

The rapid increase in the number of proteins in sequence databases and the diversity of their
functions challenge computational approaches for automated function prediction. Here, we …

Lifestyle factors, such as diet, strongly influence the structure, diversity, and composition of
the microbiome. While we have witnessed over the last several years a resurgence of interest …

For the past half-century, structural biologists relied on the notion that similar protein sequences
give rise to similar structures and functions. While this assumption has driven research …

The human microbiota has a close relationship with human disease and it remodels
components of the glycocalyx including heparan sulfate (HS). Studies of the severe acute …

Inflammatory disorders of the skin are frequently associated with inflammatory bowel diseases
(IBDs). To explore mechanisms by which these organs communicate, we performed single…

CC chemokine receptor 2 (CCR2) is a part of the chemokine receptor family, an important
class of therapeutic targets. These class A G-protein coupled receptors (GPCRs) are involved …

Inflammatory Bowel Disease (IBD) is an autoimmune condition that is observed to be associated
with major alterations in the gut microbiome taxonomic composition. Here we classify …