[HTML][HTML] Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge
SARS-CoV-2 is a viral respiratory pathogen responsible for the current global pandemic
and the disease that causes COVID-19. All current WHO approved COVID-19 vaccines are …
and the disease that causes COVID-19. All current WHO approved COVID-19 vaccines are …
[HTML][HTML] SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice
KS Lee, TY Wong, BP Russ, AM Horspool, OA Miller… - Plos one, 2022 - journals.plos.org
The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC)
that have increased transmissibility, receptor binding affinity, and other properties that …
that have increased transmissibility, receptor binding affinity, and other properties that …
Interplay of antibody and cytokine production reveals CXCL13 as a potential novel biomarker of lethal SARS-CoV-2 infection
AM Horspool, T Kieffer, BP Russ, MA DeJong, MA Wolf… - Msphere, 2021 - Am Soc Microbiol
The SARS-CoV-2 pandemic is impacting the global population. This study was designed to
assess the interplay of antibodies with the cytokine response in SARS-CoV-2 patients. We …
assess the interplay of antibodies with the cytokine response in SARS-CoV-2 patients. We …
Evaluating antibody mediated protection against Alpha, Beta, and Delta SARS-CoV-2 variants of concern in K18-hACE2 transgenic mice
TY Wong, AM Horspool, BP Russ, C Ye… - Journal of …, 2022 - Am Soc Microbiol
SARS-CoV-2 variants of concern (VoC) are impacting responses to the COVID-19 pandemic.
Here, we utilized passive immunization using human convalescent plasma (HCP) obtained …
Here, we utilized passive immunization using human convalescent plasma (HCP) obtained …
SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants of concern induce lethal disease in K18-hACE2 transgenic mice despite convalescent plasma therapy
SARS-CoV-2 variants of concern (VoCs) are impacting responses to the COVID-19 pandemic.
Here we present a comparison of the SARS-CoV-2 USA-WA1/2020 (WA-1) strain with B.…
Here we present a comparison of the SARS-CoV-2 USA-WA1/2020 (WA-1) strain with B.…
RBD-VLP vaccines adjuvanted with Alum or SWE protect K18-hACE2 mice against SARS-CoV-2 VOC challenge
The ongoing COVID-19 pandemic has contributed largely to the global vaccine disparity.
Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines …
Development of protein subunit vaccines can help alleviate shortages of COVID-19 vaccines …
[PDF][PDF] Obesity and metabolic dysfunction drive sex-associated differential disease profiles in hACE2-mice challenged with SARS-CoV-2
KS Lee, BP Russ, TY Wong, AM Horspool, MT Winters… - IScience, 2022 - cell.com
Severe outcomes from SARS-CoV-2 infection are highly associated with preexisting comorbid
conditions like hypertension, diabetes, and obesity. We utilized the diet-induced obesity (…
conditions like hypertension, diabetes, and obesity. We utilized the diet-induced obesity (…
[HTML][HTML] Passive immunization with equine RBD-specific Fab protects K18-hACE2-mice against Alpha or Beta variants of SARS-CoV-2
…, SN Rajpathak, N Kadam, TY Wong, BP Russ… - Frontiers in …, 2022 - frontiersin.org
Emergence of variants of concern (VOC) during the COVID-19 pandemic has contributed to
the decreased efficacy of therapeutic monoclonal antibody treatments for severe cases of …
the decreased efficacy of therapeutic monoclonal antibody treatments for severe cases of …
[HTML][HTML] Mannheimia haemolytica Negatively Affects Bovine Herpesvirus Type 1.1 Replication Capacity In Vitro
CA Cowick, BP Russ, AR Bales, B Nanduri, F Meyer - Microorganisms, 2022 - mdpi.com
Bovine Respiratory Disease (BRD) is a multifactorial condition affecting cattle worldwide
resulting in high rates of morbidity and mortality. The disease can be triggered by Bovine …
resulting in high rates of morbidity and mortality. The disease can be triggered by Bovine …
[HTML][HTML] Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants
There is a continued need for sarbecovirus vaccines that can be manufactured and distributed
in low- and middle-income countries (LMICs). Subunit protein vaccines are manufactured …
in low- and middle-income countries (LMICs). Subunit protein vaccines are manufactured …