User profiles for Bumsik Cho

Bumsik Cho

Department of Life Science, College of Natural Science, Hanyang University, Seoul, 04763 …
Verified email at hanyang.ac.kr
Cited by 335

A single-cell survey of Drosophila blood

SG Tattikota, B Cho, Y Liu, Y Hu, V Barrera… - Elife, 2020 - elifesciences.org
Drosophila blood cells, called hemocytes, are classified into plasmatocytes, crystal cells, and
lamellocytes based on the expression of a few marker genes and cell morphologies, which …

[HTML][HTML] Single-cell transcriptome maps of myeloid blood cell lineages in Drosophila

B Cho, SH Yoon, D Lee, F Koranteng… - Nature …, 2020 - nature.com
The Drosophila lymph gland, the larval hematopoietic organ comprised of prohemocytes and
mature hemocytes, has been a valuable model for understanding mechanisms underlying …

[HTML][HTML] Subpopulation of macrophage-like plasmatocytes attenuates systemic growth via JAK/STAT in the Drosophila fat body

M Shin, N Cha, F Koranteng, B Cho, J Shim - Frontiers in Immunology, 2020 - frontiersin.org
Drosophila hemocytes, like those of mammals, are given rise from two distinctive phases
during both the embryonic and larval hematopoiesis. Embryonically derived hemocytes, mostly …

[HTML][HTML] Molecular traces of Drosophila hemocytes reveal transcriptomic conservation with vertebrate myeloid cells

SH Yoon, B Cho, D Lee, H Kim, J Shim, JW Nam - PLoS Genetics, 2023 - journals.plos.org
Drosophila hemocytes serve as the primary defense system against harmful threats, allowing
the animals to thrive. Hemocytes are often compared to vertebrate innate immune system …

[HTML][HTML] Systemic control of immune cell development by integrated carbon dioxide and hypoxia chemosensation in Drosophila

B Cho, CM Spratford, S Yoon, N Cha… - Nature …, 2018 - nature.com
Drosophila hemocytes are akin to mammalian myeloid blood cells that function in stress and
innate immune-related responses. A multi-potent progenitor population responds to local …

[HTML][HTML] Iron homeostasis controls myeloid blood cell differentiation in Drosophila

S Yoon, B Cho, M Shin, F Koranteng, N Cha, J Shim - Molecules and cells, 2017 - Elsevier
Iron is an essential divalent ion for aerobic life. Life has evolved to maintain iron homeostasis
for normal cellular and physiological functions and therefore imbalances in iron levels …

[HTML][HTML] Intrinsic and extrinsic regulation of hematopoiesis in Drosophila

F Koranteng, B Cho, J Shim - Molecules and cells, 2022 - Elsevier
Drosophila melanogaster lymph gland, the primary site of hematopoiesis, contains myeloid-like
progenitor cells that differentiate into functional hemocytes in the circulation of pupae …

The NFκB Dif is required for behavioral and molecular correlates of sleep homeostasis in Drosophila

MK O'Hara, C Saul, A Handa, B Cho, X Zheng… - Sleep, 2024 - academic.oup.com
The nuclear factor binding the κ light chain in B-cells (NFκB) is involved in a wide range of
cellular processes including development, growth, innate immunity, and sleep. However, …

S-nitrosylation-mediated unfolded protein response maintains hematopoietic progenitors

B Cho, M Shin, E Chang, S Son, J Shim - bioRxiv, 2023 - biorxiv.org
The Drosophila lymph gland houses blood progenitors that give rise to myeloid-like blood
cells. Initially, blood progenitors proliferate, but later become quiescent to maintain …

Molecular Traces of Drosophila Hemocyte Evolution

SH Yoon, B Cho, D Lee, H Kim, J Shim, JW Nam - papers.ssrn.com
Drosophila hemocytes serve as the primary defense system required for the animals to thrive
and overcome harmful threats. These cells are often compared to cells of the vertebrate …