… through several mechanisms, including (a) allowing for expansion of pathogenic intestinal
bacteria, (b) priming the immune system for a robust pro-inflammatory response, and (c) …

… (C) Cas13a RNPs made individually with each crRNA were tested against 2.89 3 105
copies/μL (480 fM) of SARS-CoV-2 IVT N gene RNA in a total 20 μL reaction volume. Background …

Background Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF)
has the potential to identify a broad range of pathogens in a single test. Methods In a 1-year, …

Neutralizing autoantibodies against type I interferons (IFNs) have been found in some patients
with critical coronavirus disease 2019 (COVID-19), the disease caused by severe acute …

… b, c, Contour plots and histograms of CD14 and IFITM3 expression (b) and fold change in
IFITM3 expression (c) … Results in c are from two independent experiments and two different cell …

… Cells were then incubated at the permissive (33C) or restrictive (39C) temperature in the …
Cells were incubated in the presence or absence of 1 μg/ml hepcidin for 60 min at 37C, and …

… C+M ); LRTI defined by clinical criteria only (LRTI +C ); patients with noninfectious reasons
for acute respiratory failure (no-LRTI); and respiratory failure due to unknown cause (unk-LRTI…

… c The study also included human subjects for whom anti-α-galactosyl antibody levels
were correlated with malaria outcomes without direct assessment of the microbiome. …

Importance Identifying infectious causes of subacute or chronic meningitis can be challenging.
Enhanced, unbiased diagnostic approaches are needed. Objective To present a case …

… (c) Subunit packing down the 3 1 screw axis of the CHMP3 1–150 crystal lattice, with a
single CHMP3 1–150 molecule highlighted in blue. (d) Same assembly as in c but viewed …