The spinal cord contains neuronal circuits termed Central Pattern Generators (CPGs) that
coordinate rhythmic motor activities. CPG circuits consist of motor neurons and multiple …

During development, spinal motoneurons (MNs) diversify into a variety of subtypes that are
specifically dedicated to the motor control of particular sets of skeletal muscles or visceral …

Type-I interferons (IFNs) form a large family of cytokines that primarily act to control the early
development of viral infections. Typical type-I IFN genes, such as those encoding IFN-α or …

Postmitotic neurons are produced from a pool of cycling progenitors in an orderly fashion
that requires proper spatial and temporal coordination of proliferation, fate determination, …

Understanding how thousands of different neuronal types are generated in the CNS
constitutes a major challenge for developmental neurobiologists and is a prerequisite before …

Semaphorins and Plexins form ligand/receptor pairs that are crucial for a wide range of
developmental processes from cell proliferation to axon guidance. The ability of semaphorins to …

Acquisition of proper neuronal identity and position is critical for the formation of neural
circuits. In the embryonic spinal cord, cardinal populations of interneurons diversify into …

The spinal cord contains a diverse array of physiologically distinct interneuron cell types
that subserve specialized roles in somatosensory perception and motor control. The …

The Onecut (OC) transcription factors, namely Hepatocyte nuclear factor 6 (HNF-6), OC-2
and OC-3, are transcriptional activators expressed in liver, pancreas and nervous system …

Spinal ventral interneurons regulate the activity of motor neurons, thereby controlling motor
activities. Interneurons arise during embryonic development from distinct progenitor domains …