User profiles for C. C. Darie
 | Costel C. DarieProfessor of Chemistry & Biomolecular Science, Clarkson University Verified email at clarkson.edu Cited by 4239 |
[HTML][HTML] A critical review of bottom-up proteomics: the good, the bad, and the future of this field
Proteomics is the field of study that includes the analysis of proteins, from either a basic science
prospective or a clinical one. Proteins can be investigated for their abundance, variety of …
prospective or a clinical one. Proteins can be investigated for their abundance, variety of …
Zona pellucida domain proteins
▪ Abstract Many eukaryotic proteins share a sequence designated as the zona pellucida (ZP)
domain. This structural element, present in extracellular proteins from a wide variety of …
domain. This structural element, present in extracellular proteins from a wide variety of …
Investigation of stable and transient protein–protein interactions: past, present, and future
… post-translationally modified subproteomes with focus on analysis of plasma membranes
95, secretomes 93, or disulfide proteomics 92, 94 were recently published by our lab (Darie …
95, secretomes 93, or disulfide proteomics 92, 94 were recently published by our lab (Darie …
[PDF][PDF] Recent applications of polyethylene glycols (PEGs) and PEG derivatives
D Hutanu, MD Frishberg, L Guo, CC Darie - Mod. Chem. Appl, 2014 - jenkemusa.com
Numerous applications of polyethylene glycol derived polymers (PEGs) have been reported
in the scientific literature for many years. With increasing experience and comfort by …
in the scientific literature for many years. With increasing experience and comfort by …
Protein–protein interactions: switch from classical methods to proteomics and bioinformatics-based approaches
… This figure was adapted from Darie et al. [161], Woods et al. [134], and Spellman et al. …
This figure was adapted from Darie et al [161], with permission from the publisher …
This figure was adapted from Darie et al [161], with permission from the publisher …
[HTML][HTML] Applications of MALDI-MS/MS-based proteomics in biomedical research
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the
most widely used techniques in proteomics to achieve structural identification and …
most widely used techniques in proteomics to achieve structural identification and …
Potential biomarkers in psychiatry: focus on the cholesterol system
…, E Dudley, J Thome, CC Darie - Journal of cellular …, 2012 - Wiley Online Library
● Introduction ● Methods for proteomic analysis – Sample fractionation/biochemical
fractionation – MS ● The cholesterol system – Cholesterol and apolipoproteins – Cholesterol – …
fractionation – MS ● The cholesterol system – Cholesterol and apolipoproteins – Cholesterol – …
[HTML][HTML] Stable isotopic labeling by amino acids in cultured primary neurons: application to brain-derived neurotrophic factor-dependent phosphotyrosine-associated …
Cultured primary neurons are a well established model for the study of neuronal function in
vitro. Here we demonstrated that stable isotope labeling by amino acids in cell culture (SILAC…
vitro. Here we demonstrated that stable isotope labeling by amino acids in cell culture (SILAC…
A pilot proteomic analysis of salivary biomarkers in autism spectrum disorder
…, KL Wormwood, S Russell, JP Ryan, CC Darie… - Autism …, 2015 - Wiley Online Library
Autism spectrum disorder (ASD) prevalence is increasing, with current estimates at 1/68–1/50
individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments. Early …
individuals diagnosed with an ASD. Diagnosis is based on behavioral assessments. Early …
Force-induced near-infrared chromism of mechanophore-linked polymers
A near-infrared (NIR) mechanophore was developed and incorporated into a poly(methyl
acrylate) chain to showcase the first force-induced NIR chromism in polymeric materials. This …
acrylate) chain to showcase the first force-induced NIR chromism in polymeric materials. This …