User profiles for C. G. Ricci
Clarisse Gravina RicciDE Shaw Research Verified email at deshawresearch.com Cited by 1041 |
Docking studies on DNA-ligand interactions: building and application of a protocol to identify the binding mode
Despite DNA being an important target for several drugs, most of the docking programs are
validated only for proteins and their ligands. In this paper, we used AutoDock 4.0 to perform …
validated only for proteins and their ligands. In this paper, we used AutoDock 4.0 to perform …
Protospacer adjacent motif-induced allostery activates CRISPR-Cas9
CRISPR-Cas9 is a genome editing technology with major impact in life sciences. In this
system, the endonuclease Cas9 generates double strand breaks in DNA upon RNA-guided …
system, the endonuclease Cas9 generates double strand breaks in DNA upon RNA-guided …
[HTML][HTML] Molecular mechanism of peroxisome proliferator-activated receptor α activation by WY14643: a new mode of ligand recognition and receptor stabilization
Peroxisome proliferator-activated receptors (PPARs) are members of a superfamily of nuclear
transcription factors. They are involved in mediating numerous physiological effects in …
transcription factors. They are involved in mediating numerous physiological effects in …
Key role of the REC lobe during CRISPR–Cas9 activation by 'sensing','regulating', and 'locking'the catalytic HNH domain
… The GCs has been originally introduced by Ricci et al. in the study of the conformational
dynamics of the PPARγ–RXRα nuclear receptor complex (Ricci et al., 2016), and used to …
dynamics of the PPARγ–RXRα nuclear receptor complex (Ricci et al., 2016), and used to …
Deciphering off-target effects in CRISPR-Cas9 through accelerated molecular dynamics
CRISPR-Cas9 is the state-of-the-art technology for editing and manipulating nucleic acids.
However, the occurrence of off-target mutations can limit its applicability. Here, all-atom …
However, the occurrence of off-target mutations can limit its applicability. Here, all-atom …
Molecular dynamics of DNA: comparison of force fields and terminal nucleotide definitions
Despite DNA being a very important target for several proteins and drugs, molecular dynamics
simulations with nucleic acids still encompass many challenges, such as the reliability of …
simulations with nucleic acids still encompass many challenges, such as the reliability of …
Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch
JM Philpott, R Narasimamurthy, CG Ricci, AM Freeberg… - Elife, 2020 - elifesciences.org
Post-translational control of PERIOD stability by Casein Kinase 1δ and ε (CK1) plays a key
regulatory role in metazoan circadian rhythms. Despite the deep evolutionary conservation of …
regulatory role in metazoan circadian rhythms. Despite the deep evolutionary conservation of …
[PDF][PDF] PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period
PERIOD (PER) and Casein Kinase 1δ regulate circadian rhythms through a phosphoswitch
that controls PER stability and repressive activity in the molecular clock. CK1δ …
that controls PER stability and repressive activity in the molecular clock. CK1δ …
[HTML][HTML] Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex
… To filter long-distance and non-trivial correlations, we computed a correlation score per
residue that accumulates all intense and inter-domain correlations (CG ij inter > 0.6) displayed by …
residue that accumulates all intense and inter-domain correlations (CG ij inter > 0.6) displayed by …
Use of Al2O3–SnO2 as a support of Pt for selective dehydrogenation of light paraffins
AD Ballarini, CG Ricci, SR de Miguel, OA Scelza - Catalysis today, 2008 - Elsevier
The influence of the preparation methods of Al 2 O 3 –SnO 2 on the catalytic behaviour of Pt
supported on the above supports in the n-butane dehydrogenation reaction was studied. …
supported on the above supports in the n-butane dehydrogenation reaction was studied. …