Phthalate esters are widely used as plasticizers in the manufacture of products made of
polyvinyl chloride. Mono-(2-ethylhexyl)-phthalate (MEHP) induces rodent hepatocarcinogenesis …

Peroxisome proliferator-activated receptors (PPARs) are ligand-dependent transcription
factors that activate target genes involved in lipid metabolism, energy homeostasis, and cell …

Membranes are an important signalling platform in plants. The plasma membrane is the
point where information about the external environment must be converted into intracellular …

The Mediator16 (MED16; formerly termed SENSITIVE TO FREEZING6 [SFR6]) subunit of
the plant Mediator transcriptional coactivator complex regulates cold-responsive gene …

Plant cellulose microfibrils are synthesized by a process that propels the cellulose synthase
complex (CSC) through the plane of the plasma membrane. How interactions between …

Calcium has long been acknowledged as one of the most important signalling components
in plants. Many abiotic and biotic stimuli are transduced into a cellular response by temporal …

Important features of hepatic oxalate synthesis remain uncertain despite its clinical significance.
To clarify the terminal steps of the biosynthetic pathway and their modulation, we have …

Prenatal exposure to TCDD interferes with fetal development at doses lower than those
causing overt toxicity in adult animals. Exposure to TCDD during development produces …

Phthalate esters, widely used as plasticizers in the manufacture of products made of polyvinyl
chloride, induce reproductive and developmental toxicities in rodents. The mechanism that …

The common commercial use of phthalate esters has resulted in significant human exposure
to these bioactive compounds. The facts that phthalate ester metabolites, like endogenous …