Alzheimer's disease (AD) is a leading cause of dementia among elderly. Yet, its etiology
remains largely unclear. In this review, we summarize studies that associate systemic infection …

In the first part of this review, we will present evidence showing a functional double dissociation
between different structures of the medial temporal lobe in the consolidation of object …

These experiments investigated the involvement of several temporal lobe regions in consolidation
of recognition memory. Anisomycin, a protein synthesis inhibitor, was infused into the …

Long-term memories can undergo destabilization/restabilization processes, collectively called
reconsolidation. However, the parameters that trigger memory reconsolidation are poorly …

Glial glutamate transporter, GLT-1, is the major Na + -driven glutamate transporter to control
glutamate levels in synapses and prevent glutamate-induced excitotoxicity implicated in …

The majority of Alzheimer’s disease (AD) cases are late-onset and occur sporadically, however
most mouse models of the disease harbor pathogenic mutations, rendering them better …

Consolidation theory proposes that through the synthesis of new proteins recently acquired
memories are strengthened over time into a stable long-term memory trace. However, …

We have previously shown that blood astrocytic-origin extracellular vesicles (AEVs) from
Alzheimer’s disease (AD) patients contain high complement levels. To test the hypothesis that …

Alzheimer's disease ( AD ) is a progressive neurological disorder that impairs memory and
other cognitive functions in the elderly. The social and financial impacts of AD are …

MicroRNAs are a group of small RNAs that regulate diverse cellular processes including
neuronal function. Recent studies have shown that dysregulation of specific microRNAs is …