User profiles for C. M. Beaver
Christine M BeaversWest Coast Account Manager, Rigaku Americas Verified email at rigaku.com Cited by 6270 |
Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
Functional genomics approaches can overcome limitations—such as the lack of identification
of robust targets and poor clinical efficacy—that hamper cancer drug development. Here …
of robust targets and poor clinical efficacy—that hamper cancer drug development. Here …
Beaver: Nature's ecosystem engineers
… Beavers … beavers may play in the management of water resources, freshwater, and terrestrial
ecosystems, this article reviews the state‐of‐the‐art scientific understanding of the beaver …
ecosystems, this article reviews the state‐of‐the‐art scientific understanding of the beaver …
The structural chemistry of metallocorroles: combined X-ray crystallography and quantum chemistry studies afford unique insights
Although they share some superficial structural similarities with porphyrins, corroles,
trianionic ligands with contracted cores, give rise to fundamentally different transition metal …
trianionic ligands with contracted cores, give rise to fundamentally different transition metal …
[HTML][HTML] Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
…, FM Behan, T Green, J Krill-Burger, CM Beaver… - Nature …, 2019 - nature.com
Genome-scale CRISPR-Cas9 viability screens performed in cancer cell lines provide a
systematic approach to identify cancer dependencies and new therapeutic targets. As multiple …
systematic approach to identify cancer dependencies and new therapeutic targets. As multiple …
[HTML][HTML] Clonogenicity: holoclones and meroclones contain stem cells
CM Beaver, A Ahmed, JR Masters - PloS one, 2014 - journals.plos.org
… Fifteen colonies of each type were ring cloned as described above and transferred to a 25
cm 2 flask containing culture medium. Each clone was incubated until 70–90% confluent and …
cm 2 flask containing culture medium. Each clone was incubated until 70–90% confluent and …
High-pressure single-crystal structures of 3D lead-halide hybrid perovskites and pressure effects on their electronic and optical properties
… We measure a conductivity of 1.5 S/cm at 51 GPa with an activation energy for conduction
of only 13.2(3) meV, suggesting that the perovskite may be close to a semiconductor-to-metal …
of only 13.2(3) meV, suggesting that the perovskite may be close to a semiconductor-to-metal …
[HTML][HTML] X-ray diffraction under extreme conditions at the Advanced Light Source
… a DECTRIS Pilatus 1M detector (Dectris AG, Baden, Switzerland), which is mounted on a
Huber stage allowing 90 degrees of rotational freedom and translation over more than 10 cm. …
Huber stage allowing 90 degrees of rotational freedom and translation over more than 10 cm. …
[MnIII4LnIII4] Calix[4]arene Clusters as Enhanced Magnetic Coolers and Molecular Magnets
…, S Kennedy, SJ Teat, CM Beavers… - Journal of the …, 2010 - ACS Publications
… ) (10 cm 3 ) and MeOH (10 cm 3 ). Following 5 min of stirring, NEt 3 (0.2 g, 1.97 mmol) was
added dropwise, and the resulting purple solution was stirred for a further hour. X-ray quality …
added dropwise, and the resulting purple solution was stirred for a further hour. X-ray quality …
[HTML][HTML] Minimal genome-wide human CRISPR-Cas9 library
…, A Vinceti, M Sharma, DA Jackson, S Price, CM Beaver… - Genome biology, 2021 - Springer
CRISPR guide RNA libraries have been iteratively improved to provide increasingly efficient
reagents, although their large size is a barrier for many applications. We design an …
reagents, although their large size is a barrier for many applications. We design an …
Enhanced permeation arising from dual transport pathways in hybrid polymer–MOF membranes
… From our density measurements, we calculated the bulk density of UiO-66-NH 2 to be 1.53
g cm −3 , which is close to the estimated density of 1.3 g cm −3 for a perfect crystal and ideal …
g cm −3 , which is close to the estimated density of 1.3 g cm −3 for a perfect crystal and ideal …