User profiles for C. M. Beaver

Christine M Beavers

West Coast Account Manager, Rigaku Americas
Verified email at rigaku.com
Cited by 6270

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

FM Behan, F Iorio, G Picco, E Gonçalves, CM Beaver… - Nature, 2019 - nature.com
Functional genomics approaches can overcome limitations—such as the lack of identification
of robust targets and poor clinical efficacy—that hamper cancer drug development. Here …

Beaver: Nature's ecosystem engineers

RE Brazier, A Puttock, HA Graham… - Wiley …, 2021 - Wiley Online Library
Beaversbeavers may play in the management of water resources, freshwater, and terrestrial
ecosystems, this article reviews the state‐of‐the‐art scientific understanding of the beaver

The structural chemistry of metallocorroles: combined X-ray crystallography and quantum chemistry studies afford unique insights

…, AB Alemayehu, J Conradie, CM Beavers… - Accounts of chemical …, 2012 - ACS Publications
Although they share some superficial structural similarities with porphyrins, corroles,
trianionic ligands with contracted cores, give rise to fundamentally different transition metal …

[HTML][HTML] Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

…, FM Behan, T Green, J Krill-Burger, CM Beaver… - Nature …, 2019 - nature.com
Genome-scale CRISPR-Cas9 viability screens performed in cancer cell lines provide a
systematic approach to identify cancer dependencies and new therapeutic targets. As multiple …

[HTML][HTML] Clonogenicity: holoclones and meroclones contain stem cells

CM Beaver, A Ahmed, JR Masters - PloS one, 2014 - journals.plos.org
… Fifteen colonies of each type were ring cloned as described above and transferred to a 25
cm 2 flask containing culture medium. Each clone was incubated until 70–90% confluent and …

High-pressure single-crystal structures of 3D lead-halide hybrid perovskites and pressure effects on their electronic and optical properties

A Jaffe, Y Lin, CM Beavers, J Voss, WL Mao… - ACS central …, 2016 - ACS Publications
… We measure a conductivity of 1.5 S/cm at 51 GPa with an activation energy for conduction
of only 13.2(3) meV, suggesting that the perovskite may be close to a semiconductor-to-metal …

[HTML][HTML] X-ray diffraction under extreme conditions at the Advanced Light Source

CV Stan, CM Beavers, M Kunz, N Tamura - Quantum Beam Science, 2018 - mdpi.com
… a DECTRIS Pilatus 1M detector (Dectris AG, Baden, Switzerland), which is mounted on a
Huber stage allowing 90 degrees of rotational freedom and translation over more than 10 cm. …

[MnIII4LnIII4] Calix[4]arene Clusters as Enhanced Magnetic Coolers and Molecular Magnets

…, S Kennedy, SJ Teat, CM Beavers… - Journal of the …, 2010 - ACS Publications
… ) (10 cm 3 ) and MeOH (10 cm 3 ). Following 5 min of stirring, NEt 3 (0.2 g, 1.97 mmol) was
added dropwise, and the resulting purple solution was stirred for a further hour. X-ray quality …

[HTML][HTML] Minimal genome-wide human CRISPR-Cas9 library

…, A Vinceti, M Sharma, DA Jackson, S Price, CM Beaver… - Genome biology, 2021 - Springer
CRISPR guide RNA libraries have been iteratively improved to provide increasingly efficient
reagents, although their large size is a barrier for many applications. We design an …

Enhanced permeation arising from dual transport pathways in hybrid polymer–MOF membranes

NC Su, DT Sun, CM Beavers, DK Britt… - Energy & …, 2016 - pubs.rsc.org
… From our density measurements, we calculated the bulk density of UiO-66-NH 2 to be 1.53
g cm −3 , which is close to the estimated density of 1.3 g cm −3 for a perfect crystal and ideal …