Genetic variation in laboratory mice
Characterizing the patterns of genetic variation in an organism provides fundamental insight
into the evolutionary history of the organism and defines the scope and nature of studies …
into the evolutionary history of the organism and defines the scope and nature of studies …
Genome sequence, comparative analysis and haplotype structure of the domestic dog
Here we report a high-quality draft genome sequence of the domestic dog (Canis familiaris),
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …
together with a dense map of single nucleotide polymorphisms (SNPs) across breeds. The …
Efficient control of population structure in model organism association mapping
Genomewide association mapping in model organisms such as inbred mouse strains is a
promising approach for the identification of risk factors related to human diseases. However, …
promising approach for the identification of risk factors related to human diseases. However, …
[HTML][HTML] Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis
Ustilago maydis is a ubiquitous pathogen of maize and a well-established model organism
for the study of plant–microbe interactions 1 . This basidiomycete fungus does not use …
for the study of plant–microbe interactions 1 . This basidiomycete fungus does not use …
Genome sequence, comparative analysis, and population genetics of the domestic horse
We report a high-quality draft sequence of the genome of the horse (Equus caballus). The
genome is relatively repetitive but has little segmental duplication. Chromosomes appear to …
genome is relatively repetitive but has little segmental duplication. Chromosomes appear to …
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
We report a high-quality draft of the genome sequence of the grey, short-tailed opossum (Monodelphis
domestica). As the first metatherian (‘marsupial’) species to be sequenced, the …
domestica). As the first metatherian (‘marsupial’) species to be sequenced, the …
Efficient mapping of mendelian traits in dogs through genome-wide association
EK Karlsson, I Baranowska, CM Wade… - Nature …, 2007 - nature.com
With several hundred genetic diseases and an advantageous genome structure, dogs are
ideal for mapping genes that cause disease. Here we report the development of a genotyping …
ideal for mapping genes that cause disease. Here we report the development of a genotyping …
Disparities in diagnosis and access to health services for children with autism: data from the National Survey of Children's Health
…, KW Nolan, MA Thingvoll, CM Wade… - … of Developmental & …, 2008 - journals.lww.com
Objective: Earlier assessment of autism improves outcomes. In addition, children with autism
have significant need for medical care. Therefore, identification of factors associated with …
have significant need for medical care. Therefore, identification of factors associated with …
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains
A dense map of genetic variation in the laboratory mouse genome will provide insights into
the evolutionary history of the species 1 and lead to an improved understanding of the …
the evolutionary history of the species 1 and lead to an improved understanding of the …
The mosaic structure of variation in the laboratory mouse genome
CM Wade, EJ Kulbokas III, AW Kirby, MC Zody… - Nature, 2002 - nature.com
Most inbred laboratory mouse strains are known to have originated from a mixed but limited
founder population in a few laboratories 1 , 2 . However, the effect of this breeding history on …
founder population in a few laboratories 1 , 2 . However, the effect of this breeding history on …