Ca 2+ mobilization from intracellular stores represents an important cell signalling process
1 that is regulated, in mammalian cells, by inositol-1,4,5-trisphosphate (InsP 3 ), cyclic ADP …

Hypoxic chemotransduction in the carotid body requires release of excitatory transmitters
from type I cells that activate afferent sensory neurones. Transmitter release is dependent on …

… They were my (CN Wyatt) friends and were brilliant, kind and funny, I miss them enormously.
We would also like to apologize to Dr Roger Thomas, who was to our knowledge the first …

… the effects of CN − on Ψ m 3 h after the preparation of the CN − solution. Note that the CN −
… FCCP addition and removal, indicating that the CN − solution was having only a minor effect …

Specialized O 2 -sensing cells exhibit a particularly low threshold to regulation by O 2 supply
and function to maintain arterial pO 2 within physiological limits. For example, hypoxic …

… The gel slice was dehydrated in water + CH 3 CN (50:50 v/v) for 5 min. The supernatant was
… An equal volume of CH 3 CN was then added to the digest and incubated for 30 min at 30 C …

In arterial myocytes the Ca 2+ mobilizing messenger NAADP evokes spatially restricted Ca
2+ bursts from a lysosome-related store that are subsequently amplified into global Ca 2+ …

… similar component could also be induced by the L-type channel agonist Bay K8644 (Wyatt et
al. 1998), and the induced HVA current was blocked by the L-type channel antagonist …

1. Ca(2+)‐activated K+ (K+Ca) channels in neonatal rat type I carotid body cells were studied
using single channel patch clamp techniques. In outside‐out patches, using symmetrical …

Carotid body-mediated ventilatory increases in response to acute hypoxia are attenuated in
animals reared in an hypoxic environment. Normally, O2-sensitive K+ channels in …