User profiles for C. T. de Souza
Claudio T De SouzaProfessor de Clínica Médica, Universidade Federal de Juiz de Fora Verified email at ufjf.br Cited by 8607 |
Multi-regulatory network of ROS: the interconnection of ROS, PGC-1 alpha, and AMPK-SIRT1 during exercise
A Thirupathi, CT De Souza - Journal of physiology and biochemistry, 2017 - Springer
Transcriptional factors are easily susceptible to any stimuli, including exercise. Exercise can
significantly influence PGC-1 α and AMPK-SIRT1 pathway, as it is involved in the regulation …
significantly influence PGC-1 α and AMPK-SIRT1 pathway, as it is involved in the regulation …
[HTML][HTML] Multivariate optimization techniques in food analysis–A review
…, JHS Neto, CT de Souza, RAC Junior, AS Souza - Food chemistry, 2019 - Elsevier
This work presents a critical review of multivariate techniques employed for optimization of
methods developed in food analysis. A comparison between the response surface …
methods developed in food analysis. A comparison between the response surface …
Diet-induced inflammation of the hypothalamus in obesity
Dysfunction of specific hypothalamic neurons is regarded as an important mechanism
predisposing to the development of obesity. Recent studies have revealed that the consumption of …
predisposing to the development of obesity. Recent studies have revealed that the consumption of …
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
… De Souza , … De Souza … After washing, membranes were sealed in hybridization bags and
exposed to imaging plates for 1 d. After exposure, the imaging plates were scanned using a BAS…
exposed to imaging plates for 1 d. After exposure, the imaging plates were scanned using a BAS…
[HTML][HTML] IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition
Overnutrition caused by overeating is associated with insulin and leptin resistance through
IKKβ activation and endoplasmic reticulum (ER) stress in the hypothalamus. Here we show …
IKKβ activation and endoplasmic reticulum (ER) stress in the hypothalamus. Here we show …
[HTML][HTML] Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity
… were fed regular chow (CT) or high-fat diet (HF) for eight weeks and then randomly divided
into eight groups: CT mice, maintained for another eight weeks on the same CT diet; or HF …
into eight groups: CT mice, maintained for another eight weeks on the same CT diet; or HF …
[PDF][PDF] Atg5 disassociates the V1V0-ATPase to promote exosome production and tumor metastasis independent of canonical macroautophagy
…, L Meng, E Latreille, CT de Souza, D McCulloch… - Developmental cell, 2017 - cell.com
Autophagy and autophagy-related genes (Atg) have been attributed prominent roles in
tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called exosomes are also …
tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called exosomes are also …
Preventing postoperative metastatic disease by inhibiting surgery-induced dysfunction in natural killer cells
LH Tai, CT De Souza, S Bélanger, L Ly, AA Alkayyal… - Cancer research, 2013 - AACR
Natural killer (NK) cell clearance of tumor cell emboli following surgery is thought to be vital
in preventing postoperative metastases. Using a mouse model of surgical stress, we …
in preventing postoperative metastases. Using a mouse model of surgical stress, we …
Interleukin-10 is a protective factor against diet-induced insulin resistance in liver
… from livers obtained from mice fed control (CT) or high-fat (HF) diets for 8 weeks (D). IL-6 was
… mice fed control (CT) or high fat (HF) diets for 8 weeks (E). In (B–D), microphotographs and …
… mice fed control (CT) or high fat (HF) diets for 8 weeks (E). In (B–D), microphotographs and …
Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation
Lifestyle interventions including exercise programmes are cornerstones in the prevention of
obesity‐related diabetes. In this study, we demonstrate that a single bout of exercise inhibits …
obesity‐related diabetes. In this study, we demonstrate that a single bout of exercise inhibits …