User profiles for C. T. de Souza

Claudio T De Souza

Professor de Clínica Médica, Universidade Federal de Juiz de Fora
Verified email at ufjf.br
Cited by 8607

Multi-regulatory network of ROS: the interconnection of ROS, PGC-1 alpha, and AMPK-SIRT1 during exercise

A Thirupathi, CT De Souza - Journal of physiology and biochemistry, 2017 - Springer
Transcriptional factors are easily susceptible to any stimuli, including exercise. Exercise can
significantly influence PGC-1 α and AMPK-SIRT1 pathway, as it is involved in the regulation …

[HTML][HTML] Multivariate optimization techniques in food analysis–A review

…, JHS Neto, CT de Souza, RAC Junior, AS Souza - Food chemistry, 2019 - Elsevier
This work presents a critical review of multivariate techniques employed for optimization of
methods developed in food analysis. A comparison between the response surface …

Diet-induced inflammation of the hypothalamus in obesity

LA Velloso, EP Araújo, CT de Souza - Neuroimmunomodulation, 2008 - karger.com
Dysfunction of specific hypothalamic neurons is regarded as an important mechanism
predisposing to the development of obesity. Recent studies have revealed that the consumption of …

Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus

CT De Souza, EP Araujo, S Bordin, R Ashimine… - …, 2005 - academic.oup.com
De Souza , … De Souza … After washing, membranes were sealed in hybridization bags and
exposed to imaging plates for 1 d. After exposure, the imaging plates were scanned using a BAS…

[HTML][HTML] IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKβ and ER stress inhibition

…, GZ Rocha, JR Pauli, J Morari, CT de Souza… - PLoS …, 2010 - journals.plos.org
Overnutrition caused by overeating is associated with insulin and leptin resistance through
IKKβ activation and endoplasmic reticulum (ER) stress in the hypothalamus. Here we show …

[HTML][HTML] Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity

…, JC Moraes, JR Pauli, J Morari, CT de Souza… - PloS one, 2012 - journals.plos.org
… were fed regular chow (CT) or high-fat diet (HF) for eight weeks and then randomly divided
into eight groups: CT mice, maintained for another eight weeks on the same CT diet; or HF …

[PDF][PDF] Atg5 disassociates the V1V0-ATPase to promote exosome production and tumor metastasis independent of canonical macroautophagy

…, L Meng, E Latreille, CT de Souza, D McCulloch… - Developmental cell, 2017 - cell.com
Autophagy and autophagy-related genes (Atg) have been attributed prominent roles in
tumorigenesis, tumor growth, and metastasis. Extracellular vesicles called exosomes are also …

Preventing postoperative metastatic disease by inhibiting surgery-induced dysfunction in natural killer cells

LH Tai, CT De Souza, S Bélanger, L Ly, AA Alkayyal… - Cancer research, 2013 - AACR
Natural killer (NK) cell clearance of tumor cell emboli following surgery is thought to be vital
in preventing postoperative metastases. Using a mouse model of surgical stress, we …

Interleukin-10 is a protective factor against diet-induced insulin resistance in liver

…, JR Pauli, EP Araújo, JC Moraes, CT de Souza… - Journal of …, 2008 - Elsevier
… from livers obtained from mice fed control (CT) or high-fat (HF) diets for 8 weeks (D). IL-6 was
… mice fed control (CT) or high fat (HF) diets for 8 weeks (E). In (B–D), microphotographs and …

Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation

…, JR Pauli, PO Prada, CT De Souza… - The Journal of …, 2006 - Wiley Online Library
Lifestyle interventions including exercise programmes are cornerstones in the prevention of
obesity‐related diabetes. In this study, we demonstrate that a single bout of exercise inhibits …