User profiles for C. W. Tschumi
Christopher TschumiUniversity of Texas at El Paso Verified email at utep.edu Cited by 247 |
Diverse actions of the modulatory peptide neurotensin on central synaptic transmission
CW Tschumi, MJ Beckstead - European Journal of …, 2019 - Wiley Online Library
… transmission - Tschumi - 2019 - European Journal of Neuroscience - Wiley Online Library
… B receptor-mediated IPSCs in these neurons (Tschumi & Beckstead, 2018), suggesting that …
… B receptor-mediated IPSCs in these neurons (Tschumi & Beckstead, 2018), suggesting that …
[HTML][HTML] Ventral tegmental area astrocytes orchestrate avoidance and approach behavior
…, EA Szoeke, K Thangamani, CW Tschumi… - Nature …, 2019 - nature.com
The ventral tegmental area (VTA) is a heterogeneous midbrain structure, containing neurons
and astrocytes, that coordinates behaviors by integrating activity from numerous afferents. …
and astrocytes, that coordinates behaviors by integrating activity from numerous afferents. …
Translating the atypical dopamine uptake inhibitor hypothesis toward therapeutics for treatment of psychostimulant use disorders
…, AM Abramyan, AJ Avelar, CW Tschumi… - …, 2019 - nature.com
Medication-assisted treatments are unavailable to patients with cocaine use disorders. Efforts
to develop potential pharmacotherapies have led to the identification of a promising lead …
to develop potential pharmacotherapies have led to the identification of a promising lead …
Neurotensin release from dopamine neurons drives long-term depression of substantia nigra dopamine signaling
Midbrain dopamine neurons play central physiological roles in voluntary movement, reward
learning, and motivated behavior. Inhibitory signaling at somatodendritic dopamine D2 …
learning, and motivated behavior. Inhibitory signaling at somatodendritic dopamine D2 …
Autism-associated mutations in KV7 channels induce gating pore current
…, T Lantin, CW Tschumi… - Proceedings of the …, 2021 - National Acad Sciences
Autism spectrum disorder (ASD) adversely impacts >1% of children in the United States,
causing social interaction deficits, repetitive behaviors, and communication disorders. Genetic …
causing social interaction deficits, repetitive behaviors, and communication disorders. Genetic …
Progressively disrupted somatodendritic morphology in dopamine neurons in a mouse Parkinson's model
Background Parkinson's disease is characterized by the progressive loss of dopamine
neurons in the substantia nigra, leading to severe motor deficits. Although the disease likely …
neurons in the substantia nigra, leading to severe motor deficits. Although the disease likely …
Neurotensin speeds inhibition of dopamine neurons through temporal modulation of GABAA and GABAB receptor-mediated synaptic input
CW Tschumi, MJ Beckstead - Neuropharmacology, 2018 - Elsevier
Midbrain dopamine neurons play physiological roles in many processes including reward
learning and motivated behavior, and are tonically inhibited by γ-aminobutyric acid (GABA)…
learning and motivated behavior, and are tonically inhibited by γ-aminobutyric acid (GABA)…
Acute and subchronic PCP attenuate D2 autoreceptor signaling in substantia nigra dopamine neurons
E Piccart, CW Tschumi, MJ Beckstead - European …, 2019 - Elsevier
Phencyclidine (PCP) administration is commonly used to model schizophrenia in laboratory
animals. While PCP is well-characterized as an antagonist of glutamate-sensitive N-methyl-…
animals. While PCP is well-characterized as an antagonist of glutamate-sensitive N-methyl-…
A history of ethanol drinking increases locomotor stimulation and blunts enhancement of dendritic dopamine transmission by methamphetamine
CW Tschumi, AW Daszkowski, AL Sharpe… - Addiction …, 2020 - Wiley Online Library
A history of ethanol drinking increases locomotor stimulation and blunts enhancement of
dendritic dopamine transmission by methamphetamine - Tschumi - 2020 - Addiction Biology - …
dendritic dopamine transmission by methamphetamine - Tschumi - 2020 - Addiction Biology - …
Depression of substantia nigra dopamine transmission is driven by retrograde neurotensin release and is enhanced by methamphetamine self-administration
Midbrain dopamine neurons play central roles in reward learning and motivated behavior,
and inhibition at somatodendritic dopamine D2 receptor (D2R) synapses blunts …
and inhibition at somatodendritic dopamine D2 receptor (D2R) synapses blunts …