… Here we show that genome-wide chromatin architecture data, as mapped by Hi-C methods
across mammalian cell types and chromosomes, are well described by classical scaling …

… First, we compared Capture-C interaction tracks from the … c, The subtraction of WT and Pitx1
delL/delL CHi-C from … Capture-C profiles using Pitx1 as a viewpoint derived from CHi-C in …

… We review the picture of chromatin large-scale 3D organization emerging from the analysis
of Hi-C data and polymer modeling. In higher mammals, Hi-C contact maps reveal a complex …

… In the studied murine Epha4 locus, the algorithm returns n* = 21 and λ* = 1.0 in both the
published in situ Hi-C data of CH12-LX cells 23 and in our limb tissue cHi-C data. In the …

… (C) Virtual capture-C (vC) profiles using Shh promoter as viewpoint derived from cHi-C in
E10.… (D) A 3D polymer model of wildtype and ΔCTCF i4:i5 limb cHi-C data. Note the changes in …

Technology for measuring 3D genome topology is increasingly important for studying gene
regulation, for genome assembly and for mapping of genome rearrangements. Hi-C and …

… on the applications of polymer physics to model chromatin folding in order to try to make
sense of the complexity of experimental data emerging from new technologies such as Hi-C or …

… Next, to support our results based on Capture-C data and to investigate the structural … inferred
from Capture-C data correspond to the three key binding sites of the toy model (Figure 5C). …

The depth and complexity of data now available on chromosome 3D architecture, derived
by new technologies such as Hi‐C, have triggered the development of models based on …

… That information is unavailable in usual Hi-C data but can be easily extracted with our models.
The formation of strips of enhanced interaction between the region of duplication and the …