User profiles for C. Babbs

Charles Babbs

- Verified email at purdue.edu - Cited by 14551

Christian Babbs

- Verified email at imm.ox.ac.uk - Cited by 3219

Free radicals and the etiology of colon cancer

CF Babbs - Free Radical Biology and Medicine, 1990 - Elsevier
… The mechanism is well precedented in the chemical literature and is known to occur effectively
at temperatures between 30 and 60C and at pOfs as low as 10 mmHg. 2v'2s In addition to …

Oxygen radicals in ulcerative colitis

CF Babbs - Free Radical Biology and Medicine, 1992 - Elsevier
This article reviews the pathophysiologic concept that superoxide and hydrogen peroxide,
generated by activated leukocytes, together with low-molecular-weight chelate iron derived …

Characterization of the oscillometric method for measuring indirect blood pressure

…, M Voelz, C Combs, D Reiner, CF Babbs - Annals of biomedical …, 1982 - Springer
In this study, human subjects and dogs were used to determine the ability of the oscillometric
method to indicate systolic and diastolic pressure. In the human studies, the auscultatory …

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

…, S Fiddy, C Allan, AR Aricescu, M Attar, C Babbs… - Nature …, 2015 - nature.com
To assess factors influencing the success of whole-genome sequencing for mainstream
clinical diagnosis, we sequenced 217 individuals from 156 independent cases or families …

Genetic dissection of the α-globin super-enhancer in vivo

D Hay, JR Hughes, C Babbs, JOJ Davies, BJ Graham… - Nature …, 2016 - nature.com
Many genes determining cell identity are regulated by clusters of Mediator-bound enhancer
elements collectively referred to as super-enhancers. These super-enhancers have been …

Lethal hydroxyl radical production in paraquat-treated plants

CF Babbs, JA Pham, RC Coolbaugh - Plant Physiology, 1989 - academic.oup.com
Bipyridinium herbicides, including paraquat and diquat, are believed to act by generating
highly reactive, oxygen-centered free radicals within chloroplasts when treated plants are …

Pulse transit time as an indicator of arterial blood pressure

LA Geddes, MH Voelz, CF Babbs… - …, 1981 - Wiley Online Library
… Pulse-arrival time was measured from the apex of the R-wave of the ECG to the upstroke
of the carotid (C) and femoral (F) pulses (Fig. 1). The pulse-transit time (T) was measured as …

An international registry of survivors with Hb Bart's hydrops fetalis syndrome

D Songdej, C Babbs, DR Higgs - Blood, The Journal of the …, 2017 - ashpublications.org
Hemoglobin (Hb) Bart's hydrops fetalis syndrome (BHFS) resulting from α 0 -thalassemia is
considered a universally fatal disorder. However, over the last 3 decades, improvements in …

Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome

SRF Twigg, R Kan, C Babbs… - Proceedings of the …, 2004 - National Acad Sciences
… compared with the adjacent diencephalon, and it indicates the level of the section shown
in c. e, eye. (c) Section of an E10.5 embryo showing high Efnb1 transcript levels in the …

[HTML][HTML] Oscillometric measurement of systolic and diastolic blood pressures validated in a physiologic mathematical model

CF Babbs - Biomedical engineering online, 2012 - Springer
… Next to characterize the time rate of volume expansion of the artery, dV a /dt, one can regard
the artery as an elastic tube with a dynamic compliance, C a , which varies with volume and …