Zileuton: clinical implications of 5‐Lipoxygenase inhibition in severe airway disease

…, MTM De Chandt, CB Cairns - International journal of …, 2007 - Wiley Online Library
… LTA 4 is converted to leukotriene B 4 (LTB 4 ) by cytosolic LTA 4 hydrolase or to leukotriene
C 4 (LTC 4 ) by perinuclear LTC 4 synthase. LTC 4 undergoes extracellular metabolism to …

Response of the large‐scale structure of the atmosphere to global warming

GK Vallis, P Zurita‐Gotor, C Cairns… - Quarterly Journal of the …, 2015 - Wiley Online Library
This article discusses the possible response of the large‐scale atmospheric structure to a
warmer climate. Using integrations from the fifth phase of the Coupled Model Intercomparison …

Implementation of PMU technology in state estimation: an overview

R Zivanovic, C Cairns - Proceedings of IEEE. AFRICON'96, 1996 - ieeexplore.ieee.org
This paper presents different aspects of implementation of phasor measurement unit (PMU)
technology in power system static state estimation. Various options in the use of PMU …

[PDF][PDF] Ethical and scientific implications of the globalization of clinical research

…, JG McHutchison, ED Peterson, CB Cairns… - N Engl J …, 2009 - researchgate.net
… n o f C … Rowland C. Clinical trials seen shifting overseas. Int J Health 6. … Truelove C.
21st Annual report: belt tightens on big pharma. Med Ad News 2007;26:4-7. …

An integrated clinico-metabolomic model improves prediction of death in sepsis

…, GR Corey, GS Ginsburg, CB Cairns… - Science translational …, 2013 - science.org
Sepsis is a common cause of death, but outcomes in individual patients are difficult to predict.
Elucidating the molecular processes that differ between sepsis patients who survive and …

Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanism.

…, KB Rogers, MB Mitchell, EC Brew, CB Cairns… - Circulation …, 1993 - Am Heart Assoc
Preconditioning may find ready applicability in humans facing scheduled global cardiac
ischemia-reperfusion (IR) during bypass or transplantation, where such a maneuver is feasible …

Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

…, LJ Doey, S Al-Sarraj, C Chandler, B Zebian, C Cairns… - Cancer discovery, 2020 - AACR
Infant high-grade gliomas in the cerebral hemispheres comprise novel subgroups, with a
prevalence of ALK, NTRK1/2/3, ROS1 , or MET gene fusions. Kinase fusion–positive tumors …

A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected …

…, D Milzman, DF Gaieski, M Goyal, CB Cairns… - Critical care …, 2009 - journals.lww.com
… as a) temperature greater than 38C or less than 36C; b) respirations greater than 20 breaths/min
or partial pressure of carbon dioxide of less than 32 mm Hg; c) a heart rate greater than …

Markedness and the theory of syllable structure

CE Cairns, MH Feinstein - Linguistic Inquiry, 1982 - JSTOR
… Accordingly, we propose that onsets of the types (6b,c) have the following structure: … any of
the following environments: CC, C __ ##, or ## __ C. He asserts further that glides and vowels …

Host gene expression classifiers diagnose acute respiratory illness etiology

…, EB Quackenbush, SW Glickman, CB Cairns… - Science translational …, 2016 - science.org
Acute respiratory infections caused by bacterial or viral pathogens are among the most common
reasons for seeking medical care. Despite improvements in pathogen-based diagnostics…