[HTML][HTML] Telomere-to-telomere assemblies of 142 strains characterize the genome structural landscape in Saccharomyces cerevisiae

S O'donnell, JX Yue, OA Saada, N Agier, C Caradec… - Nature Genetics, 2023 - nature.com
Pangenomes provide access to an accurate representation of the genetic diversity of
species, both in terms of sequence polymorphisms and structural variants (SVs). Here we …

de novo assembly and population genomic survey of natural yeast isolates with the Oxford Nanopore MinION sequencer

…, O Beluche, C Caradec, S Davidas, C Cruaud… - …, 2017 - academic.oup.com
… About 85% of A, T, C, and G homopolymers of size 2 were present correctly in … C and G
homopolymers. For size 7 homopolymers, it was 30% for A and T homopolymers and 35% for C

Genetic background determines metabolic phenotypes in the mouse

MF Champy, M Selloum, V Zeitler, C Caradec… - Mammalian …, 2008 - Springer
To evaluate the contribution of genetic background to phenotypic variation, we compared a
large range of biochemical and metabolic parameters at different ages of four inbred mice …

Mouse functional genomics requires standardization of mouse handling and housing conditions

…, M Selloum, L Piard, V Zeitler, C Caradec… - Mammalian …, 2004 - Springer
… Whole-blood samples were centrifuged at 3000 rpm for 10 min in a refrigerated centrifuge
(4C). Samples were centrifuged within 2 h of collection to prevent possible in vitro changes. …

[HTML][HTML] Dissociation of analgesic and hormonal responses to forced swim stress using opioid receptor knockout mice

…, C Gavériaux-Ruff, A Matifas, C Caradec… - …, 2006 - nature.com
… into a water bath set at 52C. Latency for tail-flick was measured with a 10-s cutoff time. For
the hot plate test, the mouse was placed on a 52C hot plate and latencies for frontpaw licking …

[HTML][HTML] Variation of the meiotic recombination landscape and properties over a broad evolutionary distance in yeasts

C Brion, S Legrand, J Peter, C Caradec, D Pflieger… - PLoS …, 2017 - journals.plos.org
… Another hypothesis is that we enriched the instance of COs happening on the chromosome
C by selecting only full viable tetrads, as the absence of recombination on the Sakl0C-left …

142 telomere-to-telomere assemblies reveal the genome structural landscape in Saccharomyces cerevisiae

S O'Donnell, JX Yue, OA Saada, N Agier, C Caradec… - BioRxiv, 2022 - biorxiv.org
… We grew yeast cells cultures overnight at 30 C in 20 ml of YPD medium until early stationary
phase. We harvested cells by centrifugation and extracted total genomic DNA using the …

Contrasting Genomic Evolution Between Domesticated and Wild Kluyveromyces lactis Yeast Populations

…, C Bleykasten, K Freel, C Caradec… - Genome Biology and …, 2023 - academic.oup.com
… To obtain genomic DNA for 41 strains sequenced in the context of this study, isolates were
grown overnight at 30 C in 20 mL of YPD medium to early stationary phase before cells were …

Pan-transcriptome reveals a large accessory genome contribution to gene expression variation in yeast

…, F Dutreux, N Vakirlis, E Teyssonniere, C Caradec… - BioRxiv, 2023 - biorxiv.org
… Contrasting to previous observations in a yeast cross6 and recent findings in a C. elegans
population5, the set of trans eQTL detected in our large dataset are not biased toward a few …

Benefits of direct colposcopic vision for optimal LLETZ procedure: a prospective multicenter study

…, A Atallah, V Lavoue, C Caradec… - Journal of Lower …, 2016 - journals.lww.com
Objective The aim of the study was to assess whether direct colposcopic vision (DCV) of the
cervix during large loop excision of the transformation zone (LLETZ) is associated with a …