… D Skurnik and C Cywes-Bentley are inventors of intellectual properties [use of human …
As inventors of intellectual properties, C Cywes-Bentley and D Skurnik also have the right to …

… binding to wheat-germ agglutinin) overnight at 37 C or in 0.4 M periodate (destroys PNAG)
for 2 h at 37 C. After washing, cells were treated with the AF488 directly conjugated mAbs. …

Th17 immunity in the gastrointestinal tract is regulated by the intestinal microbiota composition,
particularly the presence of segmented filamentous bacteria (sfb), but the role of the …

Bacillus subtilis is intensively studied as a model organism for the development of bacterial
biofilms or pellicles. A key component is currently undefined exopolysaccharides produced …

The surface capsular polysaccharide (CP) is a virulence factor that has been used as an
antigen in several successful vaccines against bacterial pathogens. A vaccine has not yet been …

Many microbial pathogens produce a β-(1→6)–linked poly-N-acetyl-d-glucosamine (PNAG)
surface capsule, including bacterial, fungal, and protozoan cells. Broadly protective immune …

In the context of the great concern about the impact of human activities on the environment,
we studied 403 commensal Escherichia coli/Escherichia clade strains isolated from several …

… Colette Cywes-Bentley is an inventor of intellectual properties [use of human monoclonal
antibody to PNAG and use of PNAG vaccines] that are licensed by Brigham and Women’s …

The molecular basis of pathogen clone emergence is relatively poorly understood.
Acquisition of a bacteriophage encoding a previously unknown secreted phospholipase A 2 (…

Background New therapeutic targets for antibiotic-resistant bacterial pathogens are desperately
needed. The bacterial surface polysaccharide poly-β-(1-6)-N-acetyl-glucosamine (PNAG…