Parkinson’s disease and related synucleinopathies are characterized by the abnormal
accumulation of alpha-synuclein aggregates, loss of dopaminergic neurons, and gliosis of the …

Background and Aims Human intestinal organoids derived from induced pluripotent stem
cells have tremendous potential to elucidate the intestinal epithelium’s role in health and …

We leveraged a human gut-on-a-chip (Gut Chip) microdevice that enables independent control
of fluid flow and mechanical deformations to explore how physical cues and morphogen …

… Hinojosa are employees of and shareholders in Emulate, Inc. As an Associate Editor for
Clinical Pharmacology & Therapeutics, Richard Peck was not involved in the review or decision …

Successful translation of in vivo experimental data to human patients is an unmet need and
a bottleneck in the development of effective therapeutics. Organ-on-Chip technology aims to …

Species differences in brain and blood–brain barrier (BBB) biology hamper the translation of
findings from animal models to humans, impeding the development of therapeutics for brain …

Parkinson’s disease and related synucleinopathies are characterized by the abnormal
accumulation of alpha-synuclein aggregates, loss of dopaminergic neurons, and gliosis in the …

Successful translation of in vivo experimental data to human patients is an unmet need and
a bottleneck in the development of effective therapeutics. micro technology aims to address …

… Epidemiological studies have reported that exposure to toxic metals like cadmium (Cd)
may … of inflammation and oxidative stress activated by Cd at the bone level, particularly in …

Oolitic carbonates belonging to the Hauptrogenstein Formation of Bajocian (Middle Jurassic)
age have been shown to be anomalously enriched in cadmium (Cd) throughout the Jura …