[PDF][PDF] Severe COVID-19 is marked by a dysregulated myeloid cell compartment

…, E Wyler, P Georg, M Schneider, C Dang-Heine… - Cell, 2020 - cell.com
Coronavirus disease 2019 (COVID-19) is a mild to moderate respiratory tract infection, however,
a subset of patients progress to severe disease and respiratory failure. The mechanism …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

…, L Cvetkovic, VD Dang, C DangHeine… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical aspects of …

Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort …

…, A Solarek, C von Kalle, C Dang-Heine… - The Lancet …, 2021 - thelancet.com
… Severe systemic symptoms—including fatigue, myalgia, headache, feverishness or chills,
and fever higher than 38C—were most frequently reported after ChAdOx1 nCov-19 prime …

[PDF][PDF] A time-resolved proteomic and prognostic map of COVID-19

…, U Behrens, S Schmidt, M Rönnefarth, C Dang-Heine… - Cell systems, 2021 - cell.com
COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …

[HTML][HTML] Delayed antibody and T-cell response to BNT162b2 vaccination in the elderly, Germany

…, B Mühlemann, C Conrad, C Dang-Heine… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination
in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (…

IL‐15 dependent induction of IL‐18 secretion as a feedback mechanism controlling human MAIT‐cell effector functions

A Sattler, C DangHeine, P Reinke… - European journal of …, 2015 - Wiley Online Library
… 2C), we found a peak in the MAIT-cell response to bacteria between 12–18 h (not shown).
At this early time point, cytokine stimulation was not sufficient to induce IFNγ on its own in most …

[HTML][HTML] Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)

…, S Zvorc, S Schmidt, L Kretzler, C Dang-Heine… - Infection, 2020 - Springer
Purpose Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread worldwide
causing a global health emergency. Pa-COVID-19 aims to provide comprehensive data …

[HTML][HTML] BKV, CMV, and EBV interactions and their effect on graft function one year post-renal transplantation: results from a large multi-centre study

…, C Dang-Heine, N Wittenbrink, C Bauer… - …, 2018 - thelancet.com
… Patients with mismatch-based risk (seronegative recipient and seropositive donor) for
CMV or EBV as well as patients from arm C received at least a 3 months prophylaxis with …

Novel approach for improved assessment of phenotypic and functional characteristics of BKV-specific T-cell immunity

…, A Sattler, K Müller, T Schachtner, C Dang-Heine… - …, 2011 - journals.lww.com
… Incidence of multifunctional CD4+ triple interferon gamma (IFN-γ)/interleukin (IL)-2/tumor
necrosis factor-alpha (TNF-α) (A) and double IL-2/TNF-α (C) responders and magnitude of total …

[HTML][HTML] Prospective collection of blood plasma samples to identify potential biomarkers for the prehospital stroke diagnosis (ProGrEss-Bio): study protocol for a …

…, FI Kandil, K Kappert, C Dang-Heine… - Frontiers in …, 2023 - frontiersin.org
… The Tempus™ tube (3 ml) will be shaken, non-centrifugated, incubated for 2 h at room
temperature, and then stored in a freezer (at −20C). One drop of full blood is placed on a dry …