Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancer

…, L Adam, A Kamat, A Siefker-Radtke, C Dinney - Cancer and Metastasis …, 2009 - Springer
Epithelial-to-mesenchymal transition (EMT) is a process that plays essential roles in
development and wound healing that is characterized by loss of homotypic adhesion and cell …

[PDF][PDF] Focus on bladder cancer

CPN Dinney, DJ McConkey, RE Millikan, X Wu… - Cancer cell, 2004 - cell.com
C: Histologic map of cystectomy showing the distribution of preneoplastic in situ lesions
and invasive cancer. The distribution of allelic loss in the bladder mucosa is outlined by the …

Micropapillary bladder cancer: a review of the University of Texas MD Anderson Cancer Center experience with 100 consecutive patients

AM Kamat, CPN Dinney, JR Gee, HB Grossman… - Cancer, 2007 - Wiley Online Library
BACKGROUND Micropapillary bladder carcinoma is a rare variant of urothelial carcinoma.
To improve understanding of this disease, the authors performed a retrospective review of …

[PDF][PDF] Identification of distinct basal and luminal subtypes of muscle-invasive bladder cancer with different sensitivities to frontline chemotherapy

…, A Siefker-Radtke, B Czerniak, CPN Dinney… - Cancer cell, 2014 - cell.com
Muscle-invasive bladder cancers (MIBCs) are biologically heterogeneous and have widely
variable clinical outcomes and responses to conventional chemotherapy. We discovered …

[HTML][HTML] A consensus molecular classification of muscle-invasive bladder cancer

…, Q Mo, J Kardos, A Zlotta, A Hartmann, CP Dinney… - European urology, 2020 - Elsevier
Background Muscle-invasive bladder cancer (MIBC) is a molecularly diverse disease with
heterogeneous clinical outcomes. Several molecular classifications have been proposed, but …

Anti-epidermal growth factor receptor antibody C225 inhibits angiogenesis in human transitional cell carcinoma growing orthotopically in nude mice

…, BY Eve, DJ Hicklin, R Radinsky, CPN Dinney - Clinical Cancer …, 1999 - AACR
… 45C for 45 min. The slides were washed with 2 × SSC three times for 2 min each time at
45C. The samples were then incubated with avidin labeled with phosphatase for 30 min at 45C, …

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci

…, JM Yuan, DJ Hunter, M McGrath, CP Dinney… - Nature …, 2010 - nature.com
We conducted a multi-stage, genome-wide association study of bladder cancer with a
primary scan of 591,637 SNPs in 3,532 affected individuals (cases) and 5,120 controls of …

Interleukin 8 expression regulates tumorigenicity and metastases in androgen-independent prostate cancer

…, M Bar-Eli, R Radinsky, CA Pettaway, CPN Dinney - Clinical Cancer …, 2000 - AACR
… The reverse transcription reaction was performed at 42C for 50 min. PCR was performed
with 40 cycles of denaturation (94C for 1.5 min), annealing (58C for 45 s),and extension (72C

Use of the University of California Los Angeles integrated staging system to predict survival in renal cell carcinoma: an international multicenter study

…, J Tostain, W Artibani, CP Dinney… - Journal of Clinical …, 2004 - ascopubs.org
Purpose To evaluate ability of the University of California Los Angeles Integrated Staging
System (UISS) to stratify patients with localized and metastatic renal cell carcinoma (RCC) into …

Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma

…, Y Wang, J Chen, J Zhang, A Futreal, C Dinney… - Nature medicine, 2020 - nature.com
Immune checkpoint therapy is being tested in the neoadjuvant setting for patients with localized
urothelial carcinoma 1 , 2 , with one study reporting data in cisplatin-ineligible patients …