Frontotemporal dementia (FTD) refers to a group of progressive neurodegenerative disorders
with different pathological signatures, genetic variability and complex disease mechanisms…

The term “neuroacanthocytosis” is normally used to refer to autosomal recessive chorea–acanthocytosis
and X-linked McLeod syndrome, but there are other movement disorders in …

Individual risk markers for depression and anxiety disorders have been identified but the
explicit pathways that link genes and environment to these markers remain unknown. Here we …

Background Frontotemporal dementia (FTD) is a complex disorder characterised by a broad
range of clinical manifestations, differential pathological signatures, and genetic variability. …

… After an initial denaturation step at 94C for 15 min, 35 cycles of amplification consisting of
30 s at 94C, 30 s at 58C and 30 s at 72C were performed. RT–PCR products were run on 3% …

… C). Given the strong conservation of the terminal domains, the overall similarity and their …
Nevertheless, the strong conservation of the N and C termini indicates that these domains …

Child conduct problems (CPs) are a robust predictor of adult mental health; the concurrence
of callous–unemotional (CU) traits confers specific risk for psychopathy. Psychopathy may …

… In 2020, Dobson-Stone et al. identified a heterozygous missense pathogenic variant in
CYLD, M719V, as the cause of autosomal-dominant FTD and amyotrophic lateral sclerosis (ALS) …

We performed a prospective genotype-phenotype study using molecular screening and clinical
assessment to compare the severity of disease and the risk of sarcoma in 172 individuals …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping, fatal
neurodegenerative disorders in which the molecular and pathogenic basis remains poorly …