Polyester synthesis in transplastomic tobacco (Nicotiana tabacum L.): significant contents of polyhydroxybutyrate are associated with growth reduction

A Lössl, C Eibl, HJ Harloff, C Jung, HU Koop - Plant cell reports, 2003 - Springer
The pathway for synthesis of polyhydroxybutyrate (PHB), a polyester produced by three
bacterial enzymes, was transferred to the tobacco plastid genome by the biolistic transformation …

Integration of foreign sequences into the tobacco plastome via polyethylene glycol-mediated protoplast transformation

HU Koop, K Steinmüller, H Wagner, C Rößler, C Eibl… - Planta, 1996 - Springer
… 2a-c. PCR analysis of DNA from putative plastome transformants. Aliquots (8 lal) of PCR …
3 and 5, expected fragment size: 1.4 kbp; c primers 4 and 5, expected fragment sizes: 1.0 khp …

In vivo analysis of plastid psbA, rbcL and rpl32 UTR elements by chloroplast transformation: tobacco plastid gene expression is controlled by modulation of transcript …

C Eibl, Z Zou, A Beck, M Kim, J Mullet… - The Plant …, 1999 - Wiley Online Library
… plastid psbA, rbcL and rpl32 UTR elements by chloroplast transformation: tobacco plastid
gene expression is controlled by modulation of transcript levels and translation efficiency - Eibl

Inducible Trans-activation of Plastid Transgenes: Expression of the R. eutrophaphb Operon in Transplastomic Tobacco

A Lössl, K Bohmert, H Harloff, C Eibl… - Plant and Cell …, 2005 - academic.oup.com
Deleterious effects of constitutive transgene expression can occur if gene products are
harmful to the transformed plant. Constraints such as growth inhibition and male sterility have …

Nicotinic acetylcholine receptor ligands, a patent review (2006–2011)

D Gündisch, C Eibl - Expert opinion on therapeutic patents, 2011 - Taylor & Francis
… binding to rat brain α7 receptors with an IC 50 value of 6.3 nM in [ 3 H]cytisine binding assays,
and 62 was developed for in vivo imaging (PET) of brain α7 receptors when labeled with C

The stem-loop region of the tobacco psbA 5′UTR is an important determinant of mRNA stability and translation efficiency

Z Zou, C Eibl, HU Koop - Molecular genetics and genomics, 2003 - Springer
Regulation of chloroplast gene expression involves networked and concerted interactions
of nucleus-encoded factors with their target sites on untranslated regions (UTRs) of …

[HTML][HTML] Functional mapping of human dynamin-1-like GTPase domain based on x-ray structure analyses

J Wenger, E Klinglmayr, C Fröhlich, C Eibl, A Gimeno… - PloS one, 2013 - journals.plos.org
… Electron density of a 2F o -F c map is shown in grey and contoured at 1σ. The red sphere
designates the catalytic water (C). (B) GMP-PNP complex of the DNM1L GG construct. The …

Alterations of redox and iron metabolism accompany the development of HIV latency

…, G Oliva, CK Frese, A Trifunovic, B Galy, C Eibl… - The EMBO …, 2020 - embopress.org
… , the most significant enrichment was observed at 7 days post-infection (henceforth, dpi) (Fig
1A), corresponding to the peak of HIV-1 replication in our model (Fig EV1B and C). To …

The NLRP12 pyrin domain: structure, dynamics, and functional insights

AS Pinheiro, C Eibl, Z Ekman-Vural… - Journal of molecular …, 2011 - Elsevier
… Using a model-free analysis, we calculated a correlation time (τ c ) of ∼ 7 ns for NLRP12
PYD at 298 K. Comparison of the 15 N[ 1 H]-NOE data, which reports on fast timescale (…

Cytisine-based nicotinic partial agonists as novel antidepressant compounds

YS Mineur, C Eibl, G Young, C Kochevar… - … of Pharmacology and …, 2009 - ASPET
Nicotine and other nicotinic agents are thought to regulate mood in human subjects and have
antidepressant-like properties in animal models. Recent studies have demonstrated that …