User profiles for C. Fang-Yen
Christopher Fang-YenProfessor of Biomedical Engineering, Ohio State University Verified email at osu.edu Cited by 8064 |
Laser microsurgery in Caenorhabditis elegans
Laser killing of cell nuclei has long been a powerful means of examining the roles of individual
cells in C. elegans. Advances in genetics, laser technology, and imaging have further …
cells in C. elegans. Advances in genetics, laser technology, and imaging have further …
Tomographic phase microscopy
We report a technique for quantitative three-dimensional (3D) mapping of refractive index in
live cells and tissues using a phase-shifting laser interferometric microscope with variable …
live cells and tissues using a phase-shifting laser interferometric microscope with variable …
Scanner-free and wide-field endoscopic imaging by using a single multimode optical fiber
Y Choi, C Yoon, M Kim, TD Yang, C Fang-Yen… - Physical review …, 2012 - APS
A single multimode fiber is considered an ideal optical element for endoscopic imaging due
to the possibility of direct image transmission via multiple spatial modes. However, the wave …
to the possibility of direct image transmission via multiple spatial modes. However, the wave …
Optical diffraction tomography for high resolution live cell imaging
We report the experimental implementation of optical diffraction tomography for quantitative
3D mapping of refractive index in live biological cells. Using a heterodyne Mach-Zehnder …
3D mapping of refractive index in live biological cells. Using a heterodyne Mach-Zehnder …
Overcoming the diffraction limit using multiple light scattering in a highly disordered medium
Y Choi, TD Yang, C Fang-Yen, P Kang, KJ Lee… - Physical review …, 2011 - APS
We report that disordered media made of randomly distributed nanoparticles can be used to
overcome the diffraction limit of a conventional imaging system. By developing a method to …
overcome the diffraction limit of a conventional imaging system. By developing a method to …
Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans
We present an optogenetic illumination system capable of real-time light delivery with high
spatial resolution to specified targets in freely moving Caenorhabditis elegans. A tracking …
spatial resolution to specified targets in freely moving Caenorhabditis elegans. A tracking …
Illuminating neural circuits and behaviour in Caenorhabditis elegans with optogenetics
C Fang-Yen, MJ Alkema… - … Transactions of the …, 2015 - royalsocietypublishing.org
… enabled the targeted killing of specific cells in intact worms using a laser microbeam coupled
through a microscope; this approach has generated a great deal of our knowledge of C. …
through a microscope; this approach has generated a great deal of our knowledge of C. …
[HTML][HTML] Long-Term Imaging of Caenorhabditis elegans Using Nanoparticle-Mediated Immobilization
E Kim, L Sun, CV Gabel, C Fang-Yen - PloS one, 2013 - journals.plos.org
One advantage of the nematode Caenorhabditis elegans as a model organism is its
suitability for in vivo optical microscopy. Imaging C. elegans often requires animals to be …
suitability for in vivo optical microscopy. Imaging C. elegans often requires animals to be …
Biomechanical analysis of gait adaptation in the nematode Caenorhabditis elegans
C Fang-Yen, M Wyart, J Xie, R Kawai… - Proceedings of the …, 2010 - National Acad Sciences
… Here we investigate this feat by studying the undulatory movements of C. elegans in
Newtonian … Our results suggest that C. elegans locomotory gait continuously adapts to external …
Newtonian … Our results suggest that C. elegans locomotory gait continuously adapts to external …
[PDF][PDF] Functional organization of a neural network for aversive olfactory learning in Caenorhabditis elegans
… In this study, we sought to identify the neural circuits that allow C. elegans to exhibit
different olfactory preferences depending on adult-stage experience. The nematode detects …
different olfactory preferences depending on adult-stage experience. The nematode detects …