Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

…, C Graetz, A Graham, V Grummel, C Guaschino… - Nature …, 2013 - nature.com
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis

…, C Cordioli, C Scandellari, C Guaschino… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in people …

DMTs and Covid‐19 severity in MS: a pooled analysis from Italy and France

…, MG Grasso, A Guareschi, C Guaschino… - Annals of clinical …, 2021 - Wiley Online Library
We evaluated the effect of DMTs on Covid‐19 severity in patients with MS, with a pooled‐analysis
of two large cohorts from Italy and France. The association of baseline characteristics …

Long‐term outcomes of patients with cerebral vein thrombosis: a multicenter study

…, M Marietta, M Sessa, C Guaschino… - … of thrombosis and …, 2012 - Wiley Online Library
… Severe thrombophilia was defined as the presence of antithrombin, protein C or protein S
deficiency, antiphospholipid antibodies and by the concomitant presence of more than one …

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

…, F Esposito, L Ferrè, D Galimberti, C Guaschino… - BioRxiv, 2017 - biorxiv.org
We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and
68,284 control subjects and establish a reference map of the genetic architecture of MS that …

A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity

…, P Brambilla, G Liberatore, C Guaschino… - Annals of …, 2015 - Wiley Online Library
Objective A proportion of multiple sclerosis (MS) patients experience disease activity
despite treatment. The early identification of the most effective drug is critical to impact long‐term …

[HTML][HTML] Mild COVID‐19 infection in a group of teriflunomide‐treated patients with multiple sclerosis

V Mantero, D Baroncini, R Balgera, C Guaschino… - Journal of …, 2021 - Springer
We have read with interest the recent paper published in this journal by Maghzi et al.[1]
reporting a case series of five teriflunomide-treated multiple sclerosis (MS) patients who …

Symptomatic COVID-19 course and outcomes after three mRNA vaccine doses in multiple sclerosis patients treated with high-efficacy DMTs

…, C Guaschino, M Radaelli, C Cordioli… - Multiple Sclerosis …, 2023 - journals.sagepub.com
Background: Little is known about COVID-19 course and outcomes after a third booster
dose of mRNA vaccine against SARS-CoV-2 (mRNA-Vax) in patients with multiple sclerosis (…

Analysis of genes, pathways and networks involved in disease severity and age at onset in primary-progressive multiple sclerosis

…, F Clarelli, AM Osiceanu, C Guaschino… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: The role of genetic factors in influencing the clinical expression of multiple
sclerosis (MS) is unclear. Objective: The objective of this paper is to identify genes, pathways …

Signs and symptoms of COVID‐19 in patients with multiple sclerosis

…, A Guareschi, C Guaschino… - European journal of …, 2022 - Wiley Online Library
Background and purpose Clinical outcomes of multiple sclerosis (MS) patients affected by
coronavirus disease 2019 (COVID‐19) have been thoroughly investigated, but a further …